6u8p_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DNMT3B-DNMT3L IN COMPLEX WITH CPGPA DNA
reference	Song et al. 'Nat 11 3355 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=3.05, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6kdb_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6u8p_A interface=94,95,96,97,213,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVNParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtKSNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface > 6u8p_D interface=94,95,97,213,215,216,217,225, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtKSNsikqgknQlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface
interface signature	NVNPTKSN/NVPTKSNQ

Estimated binding specificities ?

readout + contact

# IC=8.936 IC/col=0.559 n_of_columns=16

specificity:

A |   0   0  96  16  16  24  24  24  24  24  24  24  72   0   0   0
C |   0   0   0   8  48  24  24  24  24  24  24  24   8   0  96  96
G |  96  96   0  16  16  24  24  24  24  24  24  24   8   0   0   0
T |   0   0   0  56  16  24  24  24  24  24  24  24   8  96   0   0

scan!

home
updated Tue Sep 10 21:24:59 2024