6u8v_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DNMT3B-DNMT3L IN COMPLEX WITH CPGPT DNA
reference	Zhang et al. 'Nat 11 3355 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6kdb_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6u8v_A interface=94,95,97,213,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtKSNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface > 6u8v_D interface=94,95,97,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtittKSNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface
interface signature	NVPTKSN/NVPKSN

Estimated binding specificities ?

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# IC=9.793 IC/col=0.612 n_of_columns=16

specificity:

A |   7   0   0   0  11  24  24  24  24  24  24  11  96  79   0   0
C |   5   0   5   0  63  24  24  24  24  24  24   5   0   5  96  96
G |  79  96   7   0  11  24  24  24  24  24  24  67   0   5   0   0
T |   5   0  84  96  11  24  24  24  24  24  24  13   0   7   0   0

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updated Thu Jul 31 02:46:00 2025