6u8w_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DNMT3B(K777A)-DNMT3L IN COMPLEX WITH CPGPT DNA
reference	Zhang et al. 'Nat 11 3355 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.95, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6u8w_A interface=94,95,97,213,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtASNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface > 6u8w_D interface=94,95,97,213,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtASNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface
interface signature	NVPTASN/NVPTASN

Estimated binding specificities ?

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# IC=7.688 IC/col=0.452 n_of_columns=17

specificity:

A |   2   0   0   5  11  24  24  24  24  24  24  24  24  61  55   0   0
C |   1   0   0   9   5  24  24  24  24  24  24  24  24   7  21  96  94
G |   1  96  96  23  23  24  24  24  24  24  24  24  24   7   9   0   1
T |  92   0   0  59  57  24  24  24  24  24  24  24  24  21  11   0   1

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updated Sat Dec 14 21:11:06 2024