6u8w_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DNMT3B(K777A)-DNMT3L IN COMPLEX WITH CPGPT DNA
reference	Zhang et al. 'Nat 11 3355 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.95, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6kdb_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6u8w_A interface=94,95,97,213,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtASNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface > 6u8w_D interface=94,95,97,213,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtASNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface
interface signature	NVPTASN/NVPTASN

Estimated binding specificities ?

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# IC=9.264 IC/col=0.545 n_of_columns=17

specificity:

A |   0   0   8   3  24  24  24  24  24  24  24   5  90  78   0   0  84
C |   0   0   8   8  24  24  24  24  24  24  24  24   4   5  96  96   2
G |  94  96   8   8  24  24  24  24  24  24  24  42   2   8   0   0   2
T |   2   0  72  77  24  24  24  24  24  24  24  25   0   5   0   0   8

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updated Tue Sep 10 21:26:28 2024