6u8w_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DNMT3B(K777A)-DNMT3L IN COMPLEX WITH CPGPT DNA
reference	Zhang et al. 'Nat 11 3355 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.95, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6kdb_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6u8w_A interface=94,95,97,213,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtASNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface > 6u8w_D interface=94,95,97,213,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtASNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface
interface signature	NVPTASN/NVPTASN

Estimated binding specificities ?

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# IC=9.430 IC/col=0.555 n_of_columns=17

specificity:

A |   0   0   2   2  24  24  24  24  24  24  24  19  78  78   0   0  87
C |   0   0  11   5  24  24  24  24  24  24  24  14  14   2  96  96   2
G |  94  96   8   2  24  24  24  24  24  24  24  49   2   5   0   0   5
T |   2   0  75  87  24  24  24  24  24  24  24  14   2  11   0   0   2

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updated Sat Dec 16 19:00:30 2023