6u8w_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DNMT3B(K777A)-DNMT3L IN COMPLEX WITH CPGPT DNA
reference	Zhang et al. 'Nat 11 3355 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.95, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6kdb_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6u8w_A interface=94,95,97,213,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtASNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface > 6u8w_D interface=94,95,97,213,215,216,217, lypaipaarrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtiTtASNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface
interface signature	NVPTASN/NVPTASN

Estimated binding specificities ?

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# IC=7.654 IC/col=0.450 n_of_columns=17

specificity:

A |   0   0   0   7  12  24  24  24  24  24  24  24  24  51  56   0   2
C |   0   0   0   9   9  24  24  24  24  24  24  24  24  17  17  96  94
G |   0  96  96  19  17  24  24  24  24  24  24  24  24  12   9   0   0
T |  96   0   0  61  58  24  24  24  24  24  24  24  24  16  14   0   0

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updated Tue Jan 6 14:07:18 2026