interface graph thumbnail
legend  pdf

structure nameHIV-1 WILD-TYPE REVERSE TRANSCRIPTASE-DNA COMPLEX WITH (-)-FTC-TP
reference'Commun 2 469 2019 Human immunodeficiency virus type 1 group M subtype B (isolate HXB2)
experimentX-ray (resolution=2.70, R-factor=?)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
reference complex7ozw_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIYPQYMCRQ/VYSKYVL

Estimated binding specificities ?

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# IC=3.634 IC/col=0.214 n_of_columns=17 specificity:   
A |   0   8  24  24   8  24  24  24  24  24  24  24  24  24  24  96  19
C |   0   8  24  24  52  24  24  24  24  24  24  24  24  24  24   0  52
G |  96  72  24  24  17  24  24  24  24  24  24  24  24  24  24   0   8
T |   0   8  24  24  19  24  24  24  24  24  24  24  24  24  24   0  17
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updated Fri Jun 26 00:55:29 2026