interface graph thumbnail
legend  pdf

structure nameHIV-1 WILD-TYPE REVERSE TRANSCRIPTASE-DNA COMPLEX WITH (-)-3TC-TP
reference'Commun 2 469 2019 Human immunodeficiency virus type 1 group M subtype B (isolate HXB2)
experimentX-ray (resolution=2.59, R-factor=?)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
reference complex7ozw_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIPYMRRQ/VMGSP

Estimated binding specificities ?

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# IC=2.635 IC/col=0.155 n_of_columns=17 specificity:   
A |   9   9  24  24  24  24  24  24  24  24  24  24  24  24  24   9   0
C |  11  11  24  24  24  24  24  24  24  24  24  24  24  24  24  67  96
G |  67   9  24  24  24  24  24  24  24  24  24  24  24  24  24   9   0
T |   9  67  24  24  24  24  24  24  24  24  24  24  24  24  24  11   0
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updated Tue Jan 6 14:16:16 2026