6vvs_FT : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A MYCOBACTERIUM SMEGMATIS RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX WITH ANTIBIOTIC SORANGICIN
reference	Campbell et al. Proc.Natl.Acad.Sci.USA 117 30423 2020
experiment	X-ray (resolution=3.11, R-factor=?)
structural superfamily	C-terminal domain of RNA polymerase alpha subunit;
reference complex	5tw1_T
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6vvs_F interface=126,127,130,133,134,147,148,151,276,277,278,279,281,282, sadsvraylkqigkvallnaeeevelakrieaglyatqklaelaekgeklpvqqrrdmqwicrdgdraknhlleanlrlvvslakrytgrgmafldliqegnlgliravekfdytkgykfstyatWWirQaiTRamadqartiripVHmvEvinklgriqrellqdlgreptpeelakemditpekvleiqqyarepisldqtigdegdsqlgdfiedseavvavdavsftllqdqlqsvletlsereagvvrlrfgltdgqprtldeigqvygvTRERiRQiesktmsklrhpsrsqvlrdyld > 6vvs_T interface=9, iddldltvRsynclkregvhtvgelvartesdlldirnfgqksidevkiklhq
interface signature	WWQTRVHETRERRQ/R

Estimated binding specificities ?

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# IC=13.948 IC/col=0.558 n_of_columns=25

specificity:

A |  96   0   0  96  24  76  24  24  24  24  24  24  24  24  12  24  24  24   6   0   0   0  60  96   0
C |   0   0  96   0  24   6  24  24  24  24  24  24  24  24  64  24  24  24   6   0   0  96  12   0   0
G |   0  96   0   0  24   8  24  24  24  24  24  24  24  24   8  24  24  24   8  96   0   0  12   0  96
T |   0   0   0   0  24   6  24  24  24  24  24  24  24  24  12  24  24  24  76   0  96   0  12   0   0

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updated Fri Jun 26 01:37:28 2026