6vvv_FT : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A MYCOBACTERIUM SMEGMATIS TRANSCRIPTION INITIATION COMPLEX WITH RIFAMPICIN-RESISTANT RNA POLYMERASE
reference	Campbell et al. Proc.Natl.Acad.Sci.USA 117 30423 2020
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	C-terminal domain of RNA polymerase alpha subunit;
reference complex	5tw1_T
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6vvv_F interface=125,126,129,132,133,146,147,150,265,275,276,277,278,280,281, adsvraylkqigkvallnaeeevelakrieaglyatqklaelaekgeklpvqqrrdmqwicrdgdraknhlleanlrlvvslakrytgrgmafldliqegnlgliravekfdytkgykfstyatWWirQaiTRamadqartiripVHmvEvinklgriqrellqdlgreptpeelakemditpekvleiqqyarepisldqtigdegdsqlgdfiedseavvavdavsftllqdqlqsvletlsereagvvrlrfgltdgqprtLdeigqvygvTRERiRQiesktmsklrhpsrsqvlrdy > 6vvv_T interface=9, iddldltvRsynclkregvhtvgelvartesdlldirnfgqksidevkiklhq
interface signature	WWQTRVHELTRERRQ/R

Estimated binding specificities ?

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# IC=12.689 IC/col=0.508 n_of_columns=25

specificity:

A |  90   0   0  96  24  79  24  24  24  24  24  24  24  24  24  24  24  24   5   0   5   0  73  96   7
C |   0   0  96   0  24   5  24  24  24  24  24  24  24  24  24  24  24  24   7   0   5  96   5   0   5
G |   1  96   0   0  24   7  24  24  24  24  24  24  24  24  24  24  24  24   5  96   7   0  11   0  84
T |   5   0   0   0  24   5  24  24  24  24  24  24  24  24  24  24  24  24  79   0  79   0   7   0   0

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updated Tue Jan 6 14:59:34 2026