6w89_GJ : 3D-footprint complex

structure name	STRUCTURE OF DNMT3A (R882H) IN COMPLEX WITH CGA DNA
reference	Anteneh et al. 'Nat 11 2294 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6pa7_K
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6w89_G interface=87,88,90,206,208,209,210,218, ekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmshlarqrllgrswsvpvirhlfaplkeyfacv > 6w89_J interface=88,89,91,207,209,211,217,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRsNsikqgKdQhfpvfmnekedilwctemervfgfpvhytdvsnmshlarqrllgrswsvpvirhlfaplkeyfacv
interface signature	IVPTRSNQ/IVPTRNKQ

Estimated binding specificities ?

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# IC=12.742 IC/col=0.708 n_of_columns=18

specificity:

A |   6   0   0  96   0   6  24  24  24  24  24  24   6  78   0   0   0  78
C |   6   0   0   0   0  78  24  24  24  24  24  24   6   6   0  96  96   6
G |   6  96  96   0   0   6  24  24  24  24  24  24  78   6   0   0   0   6
T |  78   0   0   0  96   6  24  24  24  24  24  24   6   6  96   0   0   6

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updated Tue Jan 6 15:50:23 2026