6w8b_AD : 3D-footprint complex

structure name	STRUCTURE OF DNMT3A IN COMPLEX WITH CGA DNA
reference	Anteneh et al. 'Nat 11 2294 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6pa7_K
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6w8b_A interface=88,89,91,207,209,210,211,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv > 6w8b_D interface=88,89,91,207,209,210,211,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv
interface signature	IVPTRSNQ/IVPTRSNQ

Estimated binding specificities ?

readout + contact

# IC=9.228 IC/col=0.577 n_of_columns=16

specificity:

A |   9   0  76   0   9  24  24  24  24  24  24  24  96  10   0   9
C |   0   0   0   0  57  24  24  24  24  24  24  24   0   0  96  78
G |  87  96  19   0  21  24  24  24  24  24  24  24   0   0   0   9
T |   0   0   1  96   9  24  24  24  24  24  24  24   0  86   0   0

scan!

home
updated Tue Jan 6 15:50:48 2026