6w8b_AD : 3D-footprint complex

structure name	STRUCTURE OF DNMT3A IN COMPLEX WITH CGA DNA
reference	Anteneh et al. 'Nat 11 2294 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6w8b_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6w8b_A interface=88,89,91,207,209,210,211,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv > 6w8b_D interface=88,89,91,207,209,210,211,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv
interface signature	IVPTRSNQ/IVPTRSNQ

Estimated binding specificities ?

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# IC=9.921 IC/col=0.584 n_of_columns=17

specificity:

A |   0   0  90   0  24  24  24  24  24  24  24   6  96   0   0   1  54
C |   8   0   0   0  24  24  24  24  24  24  24   2   0  20  96  82  13
G |  82  96   0   0  24  24  24  24  24  24  24  75   0   0   0   0  20
T |   6   0   6  96  24  24  24  24  24  24  24  13   0  76   0  13   9

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updated Thu Jul 31 04:18:51 2025