6w8b_AD : 3D-footprint complex

structure name	STRUCTURE OF DNMT3A IN COMPLEX WITH CGA DNA
reference	Anteneh et al. 'Nat 11 2294 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6pa7_K
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6w8b_A interface=88,89,91,207,209,210,211,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv > 6w8b_D interface=88,89,91,207,209,210,211,219, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtiTtRSNsikqgkdQhfpvfmnekedilwctemervfgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv
interface signature	IVPTRSNQ/IVPTRSNQ

Estimated binding specificities ?

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# IC=10.205 IC/col=0.600 n_of_columns=17

specificity:

A |   0   0  88   0  24  24  24  24  24  24  24   0  96   1   0   1  59
C |   7   0   0   0  24  24  24  24  24  24  24   0   0  14  96  81  14
G |  81  96   0   0  24  24  24  24  24  24  24  81   0   0   0   0  16
T |   8   0   8  96  24  24  24  24  24  24  24  15   0  81   0  14   7

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updated Fri Jun 26 02:25:58 2026