6w8d_AD : 3D-footprint complex

structure name	STRUCTURE OF DNMT3A (R882H) IN COMPLEX WITH CGT DNA
reference	Anteneh et al. 'Nat 11 2294 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6w8b_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6w8d_A interface=87,88,89,90,208,210, ekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVNParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtittRsNsikqgkdqhfpvfmnekedilwctemervfgfpvhytdvsnmshlarqrllgrswsvpvirhlfaplkeyfacv > 6w8d_D interface=88,89,91,209, aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrsvtqkhiqewgpfdlviggspcndlsIVnParkglyegtgrlffefyrllhdarpkegddrpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastvndklelqeclehgriakfskvrtittRsnsikqgkdqhfpvfmnekedilwctemervfgfpvhytdvsnmshlarqrllgrswsvpvirhlfaplkeyfacv
interface signature	IVNPRN/IVPR

Estimated binding specificities ?

contact

# IC=7.999 IC/col=0.400 n_of_columns=20

specificity:

A |  11   0  24   0  17  24  24  24  24  24  24  24  24  24  57  69   0  24   0  96
C |  17   0  24   0   7  24  24  24  24  24  24  24  24  24  13  16  96  24  96   0
G |  15  96  24  96  15  24  24  24  24  24  24  24  24  24  15  11   0  24   0   0
T |  53   0  24   0  57  24  24  24  24  24  24  24  24  24  11   0   0  24   0   0

scan!

home
updated Tue Sep 10 22:51:51 2024