6wc2_ABO : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TERNARY MEF2 CHIMERA/NKX2-5/MYOCARDIN ENHANCER DNA COMPLEX
reference	Chen et al. J.Mol.Biol. 432 5499 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.10, R-factor=?)
structural superfamily	SRF-like;
reference complex	6wc2_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6wc2_A interface=2,22, gRkkiqitrimdernrqvtftKrkfglmkkayelsvlcdceialiifnssnklfqyastdmdkvllkyteysephesrtntdiletlkrre > 6wc2_B interface=19, kiqitrimdernrqvtftKrkfglmkkayelsvlcdceialiifnssnklfqyastdmdkvllkyteysephesrtntdiletlkrre > 6wc2_O interface=42,45,46,49,50, vlfsqaqvyelerrfkqqrylsaperdqlasvlkltstqvkIwfQNrrYKskr
interface signature	RK/K/IQNYK

Estimated binding specificities ?

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# IC=6.984 IC/col=0.499 n_of_columns=14

specificity:

A |   1   0  12  24   6   7  24  24  24  24  24   6  96   0
C |  19   0  21  24  89  64  24  24  24  24  24  14   0   0
G |   0   0   6  24   1   6  24  24  24  24  24  12   0  96
T |  76  96  57  24   0  19  24  24  24  24  24  64   0   0

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updated Tue Jan 6 15:52:59 2026