6wc2_DM : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TERNARY MEF2 CHIMERA/NKX2-5/MYOCARDIN ENHANCER DNA COMPLEX
reference	Chen et al. J.Mol.Biol. 432 5499 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.10, R-factor=?)
structural superfamily	SRF-like;
reference complex	1egw_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6wc2_D interface=2,14,18,22, gRkkiqitrimdeRnrqVtftKrkfglmkkayelsvlcdceialiifnssnklfqyastdmdkvllkyteysephesrtntdiletlkrrehr > 6wc2_M interface=1,43,46,47,50, RvlfsqaqvyelerrfkqqrylsaperdqlasvlkltstqvkIwfQNrrYkskr
interface signature	RRVK/RIQNY

Estimated binding specificities ?

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# IC=12.284 IC/col=0.647 n_of_columns=19

specificity:

A |   4   7  24   0   0   0   4   6  24  24  24  24  24  24   0  96   0   4  11
C |   2  81  24  96   0   0   4  72  24  24  24  24  24  24   0   0   0   4   9
G |  86   4  24   0   0   0   7   9  24  24  24  24  24  24   0   0  96   4  67
T |   4   4  24   0  96  96  81   9  24  24  24  24  24  24  96   0   0  84   9

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updated Thu Jul 31 04:20:34 2025