interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF A TERNARY MEF2 CHIMERA/NKX2-5/MYOCARDIN ENHANCER DNA COMPLEX
referenceChen et al. J.Mol.Biol. 432 5499 2020
sourceHOMO SAPIENS
experimentX-ray (resolution=2.10, R-factor=?)
structural superfamilySRF-like;
reference complex1egw_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureR/RVK/RKIQNY

Estimated binding specificities ?

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# IC=10.859 IC/col=0.639 n_of_columns=17 specificity:   
A |  10   0  85  24  24  24  24  24  24   0  96  96  96  81  75  10   5
C |  75   0   6  24  24  24  24  24  24   0   0   0   0   0   0  10  75
G |  10   0   5  24  24  24  24  24  24  96   0   0   0  15  10  65   6
T |   1  96   0  24  24  24  24  24  24   0   0   0   0   0  11  11  10
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updated Thu Jul 31 04:20:22 2025