interface graph thumbnail
legend  pdf

structure nameYTH DOMAIN OF HUMAN YTHDC1 WITH 11MER SSDNA CONTAINING N6MA
(YTH domain-containing protein 1)
referenceHorton et al. 'Nucleic 48 10329 2020
sourceHomo sapiens
experimentX-ray (resolution=1.59, R-factor=0.223)
sequence familyYT521Blike family;
redundant complexes6wea_A 7l4x_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureLPMNKKIR

Estimated binding specificities ?

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# IC=3.278 IC/col=0.820 n_of_columns=4 specificity:   
A |   0   0  12  12
C |   0  96  12  60
G |  96   0  12  12
T |   0   0  60  12
scan!

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updated Sat Jan 10 12:36:38 2026