interface graph thumbnail
legend  pdf

structure nameTHE HOMING ENDONUCLEASE I-WCAI BOUND TO ITS DNA RECOGNITION SEQUENCE
(Probable intron-encoded endonuclease 1)
referenceNawimanage et al. J.Mol.Biol. 434 167550 2022
sourceWickerhamomyces canadensis
experimentX-ray (resolution=1.95, R-factor=0.229)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG DNA endonuclease family;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signaturePNYKLRQEYRNHVTRQDYHQNK

Estimated binding specificities ?

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# IC=14.898 IC/col=0.828 n_of_columns=18 specificity:   
A |  86   4   4  81  24   0   0   0   0   9  24  24   0   0   0   6  24  91
C |   4   9  12   4  24  96  96   0   0  14  24  24   0  96  96  86  24   0
G |   2   7   4   4  24   0   0   0  96   4  24  24   0   0   0   0  24   4
T |   4  76  76   7  24   0   0  96   0  69  24  24  96   0   0   4  24   1
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Tue Dec 19 16:15:30 2023