6x1j_A : 3D-footprint complex

structure name	THE HOMING ENDONUCLEASE I-WCAI BOUND TO ITS DNA RECOGNITION SEQUENCE (Probable intron-encoded endonuclease 1)
reference	Nawimanage et al. J.Mol.Biol. 434 167550 2022
source	Wickerhamomyces canadensis
experiment	X-ray (resolution=1.95, R-factor=0.229)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG DNA endonuclease family;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6x1j_A interface=12,13,44,46,48,50,57,59,84,86,88,89,94,96,98,100,148,149,161,163,190,191, iinkkdllglgPNsklikdykkqwttlskiqeetlignilgdvYiKkLkRnkhfllQfEwknkayiehivrvfdeyvispptlYeRkNHlgnkViTwRaQtfehkafdklgyyfmenhkkiikpdlvlnyiterslaywfmddggkwDYnkktknkslvlHtQgfkkeeveilindlnikfnlncsikfNKnkpiiyipnkdyelfynlvnpyiipemkykllfnv
interface signature	PNYKLRQEYRNHVTRQDYHQNK

Estimated binding specificities ?

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# IC=15.107 IC/col=0.839 n_of_columns=18

specificity:

A |  76   0   9  86  24   0   0   0   0   4  24  24   0   0   0   4  24  96
C |   7   9   9   4  24  96  96   0   0  24  24  24   0  96  96  81  24   0
G |   4   4   4   4  24   0   0   0  96   0  24  24   0   0   0   4  24   0
T |   9  83  74   2  24   0   0  96   0  68  24  24  96   0   0   7  24   0

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Dendrogram of similar interfaces ?

matrix format

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updated Sat Sep 14 00:44:09 2024