6x7k_ABE : 3D-footprint complex

3D-footprint cannot reliably estimate the specificity of 'beta and beta-prime subunits of DNA dependent RNA-polymerases', as these often contain single-stranded DNA molecules which accumulate many base contacts which distort the calculations.

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updated Sun Dec 15 00:12:24 2024

structure name	CRYO-EM STRUCTURE OF AN ESCHERICHIA COLI COUPLED TRANSCRIPTION- TRANSLATION COMPLEX B3 (TTC-B3) CONTAINING AN MRNA WITH A 24 NT LONG SPACER, TRANSCRIPTION FACTORS NUSA AND NUSG, AND FMET-TRNAS AT P- SITE AND E-SITE
experiment	NMR
structural superfamily	Insert subdomain of RNA polymerase alpha subunit;C-terminal domain of RNA polymerase alpha subunit;RBP11-like subunits of RNA polymerase;cAMP-binding domain-like;"Winged helix" DNA-binding domain;P-loop containing nucleoside triphosphate hydrolases;Putative DNA-binding domain;beta and beta-prime subunits of DNA dependent RNA-polymerase;Nucleic acid-binding proteins;Rho N-terminal domain-like;Probable bacterial effector-binding domain;Homeodomain-like;lambda repressor-like DNA-binding domains;CheY-like;C-terminal effector domain of the bipartite response regulators;
reference complex	3iyd_A 3iyd_H 5nss_G 6ldi_G 6vu3_A 6vz3_A 6xas_B 6xh7_H 6xl5_H 7c97_K 7vwz_G 7w5x_A 8igr_C 8jo2_H 8u3b_G 8upo_A 8y6u_I
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6x7k_A interface=149,150,174,181,182,198,200,541, vysytekkrirkdfgkrpqvldvpyllsiqldsfqkfieqdpegqygleaafrsvfpiqsysgnselqyvsyrlgepvfdvqecqirgvtysaplrvklrlviyereapegtvkdikeqevymgeiplmtdngtfvingtervivsqlHRspgvffdsdkgkthssgkvlynaRiipyrgSWldfefdpkdnlfvriDrRrklpatiilralnytteqildlffekvifeirdnklqmelvperlrgetasfdieangkvyvekgrritarhirqlekddvklievpveyiagkvvakdyidestgelicaanmelsldllaklsqsghkrietlftndldhgpyisetlrvdptndrlsalveiyrmmrpgepptreaaeslfenlffsedrydlsavgrmkfnrsllreeiegsgilskddiidvmkklidirngkgevddidhlgnrrirsvgemaenqfrvglvrveravkerlslgdldtlmpqdminakpisaavkeffgssqlsqfmdqnnplseithkrrisalgpggltreRagfevrdvhpthygrvcpietpegpniglinslsvyaqtneygfletpyrkvtdgvvtdeihylsaieegnyviaqansnldeeghfvedlvtcrskgesslfsrdqvdymdvstqqvvsvgaslipflehddanralmganmqrqavptlradkplvgtgmeravavdsgvtavakrggvvqyvdasrivikvnedemypgeagidiynltkytrsnqntcinqmpcvslgepvergdvladgpstdlgelalgqnmrvafmpwngynfedsilvservvqedrfttihiqelacvsrdtklgpeeitadipnvgeaalskldesgivyigaevtggdilvgkvtpkgetqltpeekllraifgekasdvkdsslrvpngvsgtvidvqvftrdgvekdkraleieemqlkqakkdlseelqileaglfsriravlvaggveaekldklprdrwlelgltdeekqnqleqlaeqydelkhefekkleakrrkitqgddlapgvlkivkvylavkrriqpgdkmagrhgnkgviskinpiedmpydengtpvdivlnplgvpsrmnigqilethlgmaakgigdkinamlkqqqevaklrefiqraydlgadvrqkvdlstfsdeevmrlaenlrkgmpiatpvfdgakeaeikellklgdlptsgqirlydgrtgeqferpvtvgymymlklnhlvddkmharstgsyslvtqqplggkaqfggqrfgemevwaleaygaaytlqemltvksddvngrtkmyknivdgnhqmepgmpesfnvllkeirslginieled > 6x7k_B interface=10, kkrwyvvqaFsgfegrvatslrehiklhnmedlfgevmvpteekffpgyvlvqmvmndaswhlvrsvprvmgfiggtsdrpapisdkevdaimnrlqqvgdkprpktlfepgemvrvndgpfadfngvveevdyeksrlkvsvsifgratpveldfsqvek > 6x7k_E interface=1380,240,256,259,299,302,337,411,412,775,776,1132, efdaikialaspdmirswsfgevkkpetinyrtfkperdglfcarifgpvkdyeclcgkykrlkhrgvicekcgvevtqtkvrrermghielasptahiwflkslpsrigllldmplrdiervlyfesyvvieggmtnlerqqilteeqyldaleefgdefdakmgaeaiqallksmdleqeceqlreelnetnsetkrkkltkriklleafvqsgnkpewmiltvlpvlppdlrplvpLdggrfatsdlndlyrRviNrnnrlkrlldlaapdiivrnekrmlqeavdalldngrrgRaiTgsnkrplksladmikgkqgrfrqnllgkrvdysgRsvitvgpylrlhqcglpkkmalelfkpfiygklelrglattikaakkmvereeavvwdildevirehpvllnrAPtlhrlgiqafepvliegkaiqlhplvcaaynadfdgdqmavhvpltleaqlearalmmstnnilspangepiivpsqdvvlglyymtrdcvnakgegmvltgpkeaerlyrsglaslharvkvriteyekdangelvaktslkdttvgrailwmivpkglpysivnqalgkkaiskmlntcyrilglkptvifadqimytgfayaarsgasvgiddmvipekkheiiseaeaevaeiqeqfqsglvtagerynkvidiwaaandrvskammdnlqtetvinrdgqeekqvsfnsiymmadsgargsaaqirqlagmrglmakpdgsiietpitanfreglnvlqyfisthgarkgladtalkTAnsgyltrrlvdvaqdlvvteddcgthegimmtpvieggdvkeplrdrvlgrvtaedvlkpgtadilvprntllheqwcdlleensvdavkvrsvvscdtdfgvcahcygrdlarghiinkgeaigviaaqsigepgtqltmrssiqvknkgsiklsnvksvvnssgklvitsrntelklidefgrtkesykvpygavlakgdgeqvaggetvanwdphtmpvitevsgfvrftdmidgqtitrqtdeltglsslvvldsaertaggkdlrpalkivdaqgndvlipgtdmpaqyflpgkaivqledgvqissgdtlaripqgglprvadlfearrpkepailaeisgivsfgketKgkrrlvitpvdgsdpyeemipkwrqlnvfegervergdvisdgpeaphdilrlrgvhavtryivnevqdvyrlqgvkindkhievivrqmlrkativnagssdflegeqveysrvkianreleangkvgatysrdllgitkaslatesfisaasfqettrvlteaavagkrdelrglkenvivgrlipagtgyayhqdrmrrraniksakkraiqsekarkhnasrrsmmrtfikkvyaaieagdkaAaqkafnemqpivdrqaakglihknkaarhkanltaqinkla