3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.

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updated Tue Jan 6 18:39:17 2026

structure name	STRUCTURE OF HUMAN CGAS (K394E) BOUND TO THE NUCLEOSOME (FOCUSED REFINEMENT OF CGAS-NCP SUBCOMPLEX)
source	HOMO SAPIENS
experiment	NMR
structural superfamily	Histone-fold;
reference complex	7ccr_H
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6y5e_A interface=2,3,4, pHRYrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqssavmalqeaseaylvglfedtnlaaihakrvtimpkdiqlarrirge > 6y5e_B interface= lRDNiqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 6y5e_C interface=1, Rakaksrssraglqfpvgrvhrllrkgnyaervgagapvymaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllgkvtiaqggvlpniqavllp > 6y5e_D interface= Srkesysvyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsa > 6y5e_E interface=3,4,46, phRYrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlRfqssavmalqeaseaylvglfedtnlaaihakrvtimpkdiqlarrirge > 6y5e_F interface= kvLRdniqgitkpairrlarrggvkrisgliyeetrgvlkvflenVirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 6y5e_G interface=1, Rakaksrssraglqfpvgrvhrllrkgnyaervgagapvymaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllgkvtiaqggvlpniqavllpk > 6y5e_H interface=3, rsRkesysvyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsa