| structure name | STRUCTURAL BASIS OF REACTIVATION OF ONCOGENIC P53 MUTANTS BY A SMALL MOLECULE: METHYLENE QUINUCLIDINONE (MQ). HUMAN WILD-TYPE P53DBD BOUND TO DNA AND MQ: WT-DNA-MQ (II) (Cellular tumor antigen p53) |
| reference | Diskin-Posner et al. 'Nat 12 7057 2021 |
| source | Homo sapiens |
| experiment | X-ray (resolution=1.32, R-factor=0.142) |
| structural superfamily | p53-like transcription factors; |
| sequence family | P53 DNAbinding domain; |
| redundant complexes | 5mcv 5mcw 5mf7 7eeu 6fj5 2ata 3d0a 3kz8 5mg7 6znc 2ady 2ac0 3igk 3igl 4hje 4ibu 4ibv 4ibw 7b46 7b49 7b4a 2ahi 7b4d 7b4e 7b4f 7b4g 7b4h 5lgy 5mct 3kmd 5mcu 1tsr 1tup 7eds |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence |
No structural evidence for specific binding to DNA (<4 informative columns)
Dendrogram of similar interfaces ?
matrix formathome
updated Mon Dec 18 19:46:41 2023