7bef_ACDFG : 3D-footprint complex

structure name	STRUCTURES OF CLASS II BACTERIAL TRANSCRIPTION COMPLEXES
source	ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / KLEBSIELLA PNEUMONIAE / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12)
experiment	NMR
structural superfamily	Insert subdomain of RNA polymerase alpha subunit;C-terminal domain of RNA polymerase alpha subunit;RBP11-like subunits of RNA polymerase;
reference complex	3iyd_A 6psq_M 7c97_K 8y6u_I
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7bef_A interface= teflkprlvdieqvssthakvtleplergfghtlgnalrrillssmpgcavteveidgvlheystkegvqedileillnlkglavrvqgkdeviltlnksgigpvtaadithdgdveivkpqhvichltdenasismrikvqrgrgyvpastrihseederpigrllvdacyspveriaynveaarveqrtdldklviemetngtidpeeairraatilaeqleafvdlrfdpillrpvddleltvrsanclkaeaihyigdlvqrtevellktpnlgkkslteikdvlasrglslgmrlenwpp > 7bef_C interface=149,173,175,180,181,197,198,365,369,392,471,502,512,539,540, ysytekkrirkdfgkrpqvldvpyllsiqldsfqkfieqdpegqygleaafrsvfpiqsysgnselqyvsyrlgepvfdvqecqirgvtysaplrvklrlviyereapegtvkdikeqevymgeiplmtdngtfvingtervivsqlhRspgvffdsdkgkthssgkvlynaRiIpyrgSWldfefdpkdnlfvriDRrrklpatiilralnytteqildlffekvifeirdnklqmelvperlrgetasfdieangkvyvekgrritarhirqlekddvklievpveyiagkvvakdyidestgelicaanmelsldllaklsqsghkrietlftndldhgpyisetlrvdptndrlsalveiYrmmRpgepptreaaeslfenlffsedRydlsavgrmkfnrsllreeiegsgilskddiidvmkklidirngkgevddidhlgnrrirsvgemaenqfrvglvrveRavkerlslgdldtlmpqdminakpisaavkEffgssqlsqFmdqnnplseithkrrisalgpggltrERagfevrdvhpthygrvcpietpegpniglinslsvyaqtneygfletpyrkvtdgvvtdeihylsaieegnyviaqansnldeeghfvedlvtcrskgesslfsrdqvdymdvstqqvvsvgaslipflehddanralmganmqrqavptlradkplvgtgmeravavdsgvtavakrggvvqyvdasrivikvnedemypgeagidiynltkytrsnqntcinqmpcvslgepvergdvladgpstdlgelalgqnmrvafmpwngynfedsilvservvqedrfttihiqelacvsrdtklgpeeitadipnvgeaalskldesgivyigaevtggdilvgkvtpkgetqltpeekllraifgekasdvkdsslrvpngvsgtvidvqvftrdgvekdkraleieemqlkqakkdlseelqileaglfsriravlvaggveaekldklprdrwlelgltdeekqnqleqlaeqydelkhefekkleakrrkitqgddlapgvlkivkvylavkrriqpgdkmagrhgnkgviskinpiedmpydengtpvdivlnplgvpsrmnigqilethlgmaakgigdkinamlkqqqevaklrefiqraydlgadvrqkvdlstfsdeevmrlaenlrkgmpiatpvfdgakeaeikellklgdlptsgqirlydgrtgeqferpvtvgymymlklnhlvddkmharstgsyslvtqqplggkaqfggqrfgemevwaleaygaaytlqemltvksddvngrtkmyknivdgnhqmepgmpesfnvllkeirslginielede > 7bef_D interface=245,306,412,413,776,777, eefdaikialaspdmirswsfgevkkpetinyrtfkperdglfcarifgpvkdyeclcgkykrlkhrgvicekcgvevtqtkvrrermghielasptahiwflkslpsrigllldmplrdiervlyfesyvvieggmtnlerqqilteeqyldaleefgdefdakmgaeaiqallksmdleqeceqlreelnetnsetkrkkltkriklleafvqsgnkpewmiltvlpvlppdlrplvpldggRfatsdlndlyrrvinrnnrlkrlldlaapdiivrnekrmlqeavdalldngrrgraitgsNkrplksladmikgkqgrfrqnllgkrvdysgrsvitvgpylrlhqcglpkkmalelfkpfiygklelrglattikaakkmvereeavvwdildevirehpvllnrAPtlhrlgiqafepvliegkaiqlhplvcaaynadfdgdqmavhvpltleaqlearalmmstnnilspangepiivpsqdvvlglyymtrdcvnakgegmvltgpkeaerlyrsglaslharvkvriteyekdangelvaktslkdttvgrailwmivpkglpysivnqalgkkaiskmlntcyrilglkptvifadqimytgfayaarsgasvgiddmvipekkheiiseaeaevaeiqeqfqsglvtagerynkvidiwaaandrvskammdnlqtetvinrdgqeekqvsfnsiymmadsgargsaaqirqlagmrglmakpdgsiietpitanfreglnvlqyfisthgarkgladtalkTAnsgyltrrlvdvaqdlvvteddcgthegimmtpvieggdvkeplrdrvlgrvtaedvlkpgtadilvprntllheqwcdlleensvdavkvrsvvscdtdfgvcahcygrdlarghiinkgeaigviaaqsigepgtqltmrtfhiggaasraaaessiqvknkgsiklsnvksvvnssgklvitsrntelklidefgrtkesykvpygavlakgdgeqvaggetvanwdphtmpvitevsgfvrftdmidgqtitrqtdeltglsslvvldsaertaggkdlrpalkivdaqgndvlipgtdmpaqyflpgkaivqledgvqissgdtlaripqesggtkditgglprvadlfearrpkepailaeisgivsfgketkgkrrlvitpvdgsdpyeemipkwrqlnvfegervergdvisdgpeaphdilrlrgvhavtryivnevqdvyrlqgvkindkhievivrqmlrkativnagssdflegeqveysrvkianreleangkvgatysrdllgitkaslatesfisaasfqettrvlteaavagkrdelrglkenvivgrlipagtgyayhqdrmrrraag > 7bef_F interface=21,24,27,32,38,266,268,269,275,276,277,279,280,306,308,311,312,313,315,316,320,324,326,338,341,344,347,351,385,386,388,392,394,399,400,405,467,471, aaaqvlssveseigrttdpvRmyMreMgtveLltregEidiakriedginqvqcsvaeypeaitylleqydrveaeearlsdlitgfvdpnaesidpelarekfaelraqyvvtrdtikakgrshataqeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemveaNlRLvisiaKKYtNRglqfldliqegniglmkavdkfeyrRgYkfSTYaTWwirQaitRsIadqartiripvHmiEtiNklNrisRqmlqemgreptpeelaermlmpedkirkvlkiaKEpIsmeTpIgddeDShlgdFiedttlelpldsatteslraathdvlagltareakvlrmrfgidmntdytleevgkqfdvtReriRqieakalrklrhpsrsevlrsfldd > 7bef_G interface=35,36,39,40,85,86,90,94, tisaqvidtivewiddnlhqplriddiarhagysKWhlQRlflqykgeslgryirerklllaardlrdtdqrvydiclkygfdsQQtftRvftRtfnqppgayrke
interface signature	/RRISWDRYRRREFER/RNAPTA/RMMLENRLKKYNRRYSTYTWQRIHENNRKEITIDSFRR/KWQRQQRR

Estimated binding specificities ?

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# IC=40.111 IC/col=0.757 n_of_columns=53

specificity:

A |   0  96   0   0  24  24  24  24  24  90   9   5  96   0  80  90  90  96  24  24  24  24  24  24  24  24  24  24  24  24  24   0  24   5  14  96   0   0  96   0  96  96   0  96   5  96   0   0   0   1   0   0   0
C |   0   0   0  96  24  24  24  24  24   1  10   6   0  96   8   1   4   0  24  24  24  24  24  24  24  24  24  24  24  24  24   0  24  78   7   0  96   0   0   0   0   0   0   0  82   0  96   0   0   4   0  96   0
G |   0   0  96   0  24  24  24  24  24   1   9  80   0   0   3   4   1   0  24  24  24  24  24  24  24  24  24  24  24  24  24   0  24   5  66   0   0   0   0  96   0   0   0   0   6   0   0   0  96   1  96   0   0
T |  96   0   0   0  24  24  24  24  24   4  68   5   0   0   5   1   1   0  24  24  24  24  24  24  24  24  24  24  24  24  24  96  24   8   9   0   0  96   0   0   0   0  96   0   3   0   0  96   0  90   0   0  96

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updated Tue Jan 6 20:32:19 2026