7c97_CDFK : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF AN ESCHERICHIA COLI RNAP-PROMOTER OPEN COMPLEX (RPO) WITH SSPA
source	ESCHERICHIA COLI / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12)
experiment	NMR
structural superfamily	Insert subdomain of RNA polymerase alpha subunit;C-terminal domain of RNA polymerase alpha subunit;RBP11-like subunits of RNA polymerase;
reference complex	3iyd_A 7c97_K 8y6u_I
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7c97_C interface=149,180,181,197,365,369,372,443,536,540,544,545, ysytekkrirkdfgkrpqvldvpyllsiqldsfqkfieqdpegqygleaafrsvfpiqsysgnselqyvsyrlgepvfdvqecqirgvtysaplrvklrlviyereapegtvkdikeqevymgeiplmtdngtfvingtervivsqlhRspgvffdsdkgkthssgkvlynariipyrgSWldfefdpkdnlfvriDrrrklpatiilralnytteqildlffekvifeirdnklqmelvperlrgetasfdieangkvyvekgrritarhirqlekddvklievpveyiagkvvakdyidestgelicaanmelsldllaklsqsghkrietlftndldhgpyisetlrvdptndrlsalveiYrmmRpgEpptreaaeslfenlffsedrydlsavgrmkfnrsllreeiegsgilskddiidvmkklidirngkgevddIdhlgnrrirsvgemaenqfrvglvrveravkerlslgdldtlmpqdminakpisaavkeffgssqlsqfmvqnnplseithkrrisalgpggLtreRagfEVrdvhpthygrvcpietpegpniglinslsvyaqtneygfletpyrkvtdgvvtdeihylsaieegnyviaqansnldeeghfvedlvtcrskgesslfsrdqvdymdvstqqvvsvgaslipflehddanralmganmqrqavptlradkplvgtgmeravavdsgvtavakrggvvqyvdasrivikvnedemypgeagidiynltkytrsnqntcinqmpcvslgepvergdvladgpstdlgelalgqnmrvafmpwngynfedsilvservvqedrfttihiqelacvsrdtklgpeeitadipnvgeaalskldesgivyigaevtggdilvgkvtpkgetqltpeekllraifgekasdvkdsslrvpngvsgtvidvqvftrdgvekdkraleieemqlkqakkdlseelqileaglfsriravlvaggveaekldklprdrwlelgltdeekqnqleqlaeqydelkhefekkleakrrkitqgddlapgvlkivkvylavkrriqpgdkmagrhgnkgviskinpiedmpydengtpvdivlnplgvpsrmnigqilethlgmaakgigdkinamlkqqqevaklrefiqraydlgadvrqkvdlstfsdeevmrlaenlrkgmpiatpvfdgakeaeikellklgdlptsgqirlydgrtgeqferpvtvgymymlklnhlvddkmharstgsyslvtqqplggkaqfggqrfgemevwaleaygaaytlqemltvksddvngrtkmyknivdgnhqmepgmpesfnvllkeirslginielede > 7c97_D interface= teefdaikialaspdmirswsfgevkkpetinyrtfkperdglfcarifgpvkdyeclcgkykrlkhrgvicekcgvevtqtkvrrermghielasptahiwflkslpsrigllldmplrdiervlyfesyvvieggmtnlerqqiltEeqyldaleefgdefdakmgaeaiqallksmDLeqeceqlreelnetnSetkrkkltkriklleafvqsgnkpewmiltvlpvlppdlrplvpldggrfatsdlndlyrrvinrnnrlkrlldlaapdiivrnekrmlqeavdalldngrrgraitgsnkrplksladmikgkqgrfrqnkrvdysgrsvitvgpylrlhqcglpkkmalelfkpfIygkLelRglattikaakkmvereeavvwdildevirehpvllnraptlhrlgiqafepvliegkaiqlhplvcaaynAdfdgdqmavhvpltleaqlearalmmstnnilspangepiivpsqdvvlglyymtrdcvnakgegmvltgpkeaerlyrsglaslharvkvrIteyEkdaNGelvaktslkdttvgrailwmivpkglpysivnqalgkkaiskmlntcyrilglkptvifadqimytgfayaarsgasvgiddmvipekkheiiseaeaevaeiqeqfqsglvtagerynkvidiwaaandrvskammdnlqtetvinrdgqeekqvsfnsiymmadsgargsaaqirqlagmrglmakpdgsiietpitanfreglnvlqyfisthgarkgladtalktansgyltrrlvdvaqdlvvteddcgthegimmtpvieggdvkeplrdrvlgrvtaedvlkpgtadilvprntllheqwcdlleensvdavkvrsvvscdtdfgvcahcygrdlarghiinkgeaigviaaqsigepgtqltmaaaessiqvknkgsiklsnvksvvnssgklvitsrntelklidefgrtkesykvpygavlakgdgeqvaggetvanwdphtmpvitevsgfvrftdmidgqtitrqtdeltglsslvvldsaertaggkdlrpalkivdaqgndvlipgtdmpaqyflpgkaivqledgvqissgdtlaripqesggtkditgglprvadlfearrpkepailaeisgivsfgketkgkrrlvitpvpyeemipkwrqlnvfegervergdvisdgpeaphdilrlrgvhavtryivnevqdvyrlqgvkindkhievivrqmlrkativnagssdflegeqveysrvkianreleangkatysrdllgitkaslatesfisaasfqettrvlteaavagkrdelrglkenvivgrlipagtgyayhqdrmrrraag > 7c97_F interface=9,10,13,16,21,27,243,245,246,254,257,280,283,285,288,289,290,292,293,294,296,297,300,301,314,315,325,445,448, eigrttdpVRmyMreMgtveLltregEidiakriedginqvqcsvaeypeaitylleqydrveaeearlsdlitgfvddpelarekfaelraqyvvtrdtikataqeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemveaNlRLvisiakkYtnRglqfldliqegniglmkavdkfEyrRgYkfSTYaTWWiRQaiTRsiadqartiripVHmietinklnRisrqmlqemgreptpeelaermlmpedkirkvlkiakepismetpigddedshlgdfiedttlelpldsatteslraathdvlagltareakvlrmrfgidmntdytleevgkqfdvtrEriRqieakalrklrhpsrsevlrsfld > 7c97_K interface= dpillrpvDDleLtvRsancLkaeaiHyigdlvqrtevelkslteikdvlasrglslgmrlenwppa
interface signature	RSWDYREILREV/EDLSILRAIENG/VRMMLENRLYRERYSTYTWWRQTRVHRER/DDLRLH

Estimated binding specificities ?

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# IC=19.617 IC/col=0.577 n_of_columns=34

specificity:

A |   0  73  24  24  24  24  24  24  24  24  24  24  24  24  24   7  24   0   0   0  96  24  24  96   0   0   0   7  96  24   0   0   0   7
C |   0   9  24  24  24  24  24  24  24  24  24  24  24  24  24   9  24   0  96   0   0  24  24   0   0   0   0   9   0  24  96   0   0   7
G |  96   7  24  24  24  24  24  24  24  24  24  24  24  24  24   7  24   0   0   0   0  24  24   0   0  96  96  73   0  24   0   0  96   7
T |   0   7  24  24  24  24  24  24  24  24  24  24  24  24  24  73  24  96   0  96   0  24  24   0  96   0   0   7   0  24   0  96   0  75

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updated Sun Dec 15 03:12:42 2024