7chw_CDFK : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF AN ESCHERICHIA COLI RNAP-PROMOTER OPEN COMPLEX (RPO)
source	ESCHERICHIA COLI / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12)
experiment	NMR
structural superfamily	Insert subdomain of RNA polymerase alpha subunit;C-terminal domain of RNA polymerase alpha subunit;RBP11-like subunits of RNA polymerase;
reference complex	3iyd_A 6psq_M 7c97_K 8y6u_I
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7chw_C interface=149,181,196,197,364,368,371,372,442,448,535,539,544, ysytekkrirkdfgkrpqvldvpyllsiqldsfqkfieqdpegqygleaafrsvfpiqsysgnselqyvsyrlgepvfdvqecqirgvtysaplrvklrlviyereapegtvkdikeqevymgeiplmtdngtfvingtervivsqlhRspgvffdsdkgkthssgkvlynariipyrgsWldfefdpkdnlfvrDRrrklpatiilralnytteqildlffekvifeirdnklqmelvperlrgetasfdieangkvyvekgrritarhirqlekddvklievpveyiagkvvakdyidestgelicaanmelsldllaklsqsghkrietlftndldhgpyisetlrvdptndrlsalveiYrmmRpgEPptreaaeslfenlffsedrydlsavgrmkfnrsllreeiegsgilskddiidvmkklidirngkgevddIdhlgnRrirsvgemaenqfrvglvrveravkerlslgdldtlmpqdminakpisaavkeffgssqlsqfmvqnnplseithkrrisalgpggLtreRagfeVrdvhpthygrvcpietpegpniglinslsvyaqtneygfletpyrkvtdgvvtdeihylsaieegnyviaqansnldeeghfvedlvtcrskgesslfsrdqvdymdvstqqvvsvgaslipflehddanralmganmqrqavptlradkplvgtgmeravavdsgvtavakrggvvqyvdasrivikvnedemypgeagidiynltkytrsnqntcinqmpcvslgepvergdvladgpstdlgelalgqnmrvafmpwngynfedsilvservvqedrfttihiqelacvsrdtklgpeeitadipnvgeaalskldesgivyigaevtggdilvgkvtpkgetqltpeekllraifgekasdvkdsslrvpngvsgtvidvqvftrdgvekdkraleieemqlkqakkdlseelqileaglfsriravlvaggveaekldklprdrwlelgltdeekqnqleqlaeqydelkhefekkleakrrkitqgddlapgvlkivkvylavkrriqpgdkmagrhgnkgviskinpiedmpydengtpvdivlnplgvpsrmnigqilethlgmaakgigdkinamlkqqqevaklrefiqraydlgadvrqkvdlstfsdeevmrlaenlrkgmpiatpvfdgakeaeikellklgdlptsgqirlydgrtgeqferpvtvgymymlklnhlvddkmharstgsyslvtqqplggkaqfggqrfgemevwaleaygaaytlqemltvksddvngrtkmyknivdgnhqmepgmpesfnvllkeirslginielede > 7chw_D interface=198, teefdikialaspdmirswsfgevkkpetinyrtfkperdglfcarifgpvkdyeclcgkykrlkhrgvicekcgvevtqtkvrrermghielasptahiwflkslpsrigllldmplrdiervlyfesyvvieggmtnlerqqilteeqyldaleefgdefdakmgaeaiqallksmdleqeceqlreelnetnseTkrkkltkriklleafvqsgnkpewmiltvlpvlppdlrplvpldggrfatsdlndlyrrvinrnnrlkrlldlaapdiivrnekrmlqeavdalldngrrgraitgsnkrplksladmikgkqgrfrqngkrvdysgrsvitvgpylrlhqcglpkkmalelfkpfiygklelrglattikaakkmvereeavvwdildevirehpvllnraptlhrlgiqafepvliegkaiqlhplvcaaynadfdgdqmavhvpltleaqlearalmmstnnilspangepiivpsqdvvlglyymtrdcvnakgegmvltgpkeaerlyrsglaslharvkvriteyekdangelvaktslkdttvgrailwmivpkglpysivnqalgkkaiskmlntcyrilglkptvifadqimytgfayaarsgasvgiddmvipekkheiiseaeaevaeiqeqfqsglvtagerynkvidiwaaandrvskammdnlqtetvinrdgqeekqvsfnsiymmadsgargsaaqirqlagmrglmakpdgsiietpitanfreglnvlqyfisthgarkgladtalktansgyltrrlvdvaqdlvvteddcgthegimmtpvieggdvkeplrdrvlgrvtaedvlkpgtadilvprntllheqwcdlleensvdavkvrsvvscdtdfgvcahcygrdlarghiinkgeaigviaaqsigepgtqltmaaaessiqvknkgsiklsnvksvvnssgklvitsrntelklidefgrtkesykvpygavlakgdgeqvaggetvanwdphtmpvitevsgfvrftdmidgqtitrqtdeltglsslvvldsaertaggkdlrpalkivdaqgndvlipgtdmpaqyflpgkaivqledgvqissgdtlaripqesggtkditgglprvadlfearrpkepailaeisgivsfgketkgkrrlvitpvpyeemipkwrqlnvfegervergdvisdgpeaphdilrlrgvhavtryivnevqdvyrlqgvkindkhievivrqmlrkativnagssdflegeqveysrvkianreleangkatysrdllgitkaslatesfisaasfqettrvlteaavagkrdelrglkenvivgrlipagtgyayhqdrmrrraag > 7chw_F interface=9,10,13,14,21,27,245,246,254,257,279,280,283,285,288,289,290,292,293,294,297,300,315,325,433,434,444,445,448,449, eigrttdpVRmyMRemgtveLltregEidiakriedginqvqcsvaeypeaitylleqydrveaeearlsdlitgfvddpelarekfaelraqyvvtrdtikataqeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemveanlRLvisiakkYtnRglqfldliqegniglmkavdkFEyrRgYkfSTYaTWWirQaiTrsiadqartiripvHmietinklnRisrqmlqemgreptpeelaermlmpedkirkvlkiakepismetpigddedshlgdfiedttlelpldsatteslraathdvlagltareakvlrmrfgidmntdytLEevgkqfdvtREriRQieakalrklrhpsrsevlrsfld > 7chw_K interface=16,41, dpillrpvddleltvRsanclkaeaihyigdlvqrtevelKslteikdvlasrglslgmrlenwppa
interface signature	RWDRYREPIRLRV/T/VRMRLERLYRFERYSTYTWWQTHRLERERQ/RK

Estimated binding specificities ?

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# IC=24.478 IC/col=0.556 n_of_columns=44

specificity:

A |   4   0   0   4  24  96   0   0   0   0   0  24  24   0  96   4  24  24  24  91  24  24  24  24  24  24  24  24  24  24  24  24   4   4   0   0  96  24  24  24  24  24   0   4
C |  81  96   0   4  24   0   0  96  96   0   0  24  24   0   0   4  24  24  24   4  24  24  24  24  24  24  24  24  24  24  24  24   7   4   0  96   0  24  24  24  24  24   0   7
G |   4   0   0  81  24   0   0   0   0  96   0  24  24   0   0  81  24  24  24   0  24  24  24  24  24  24  24  24  24  24  24  24   4  84   0   0   0  24  24  24  24  24   0   4
T |   7   0  96   7  24   0  96   0   0   0  96  24  24  96   0   7  24  24  24   1  24  24  24  24  24  24  24  24  24  24  24  24  81   4  96   0   0  24  24  24  24  24  96  81

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updated Thu Jul 31 09:14:41 2025