7d2l_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE CAS12I1 R-LOOP COMPLEX BEFORE TARGET DNA CLEAVAGE (12I1-D647A)
reference	OuYang et al. 'Nat 12 3476 2021
source	LACHNOSPIRACEAE BACTERIUM ND2006
experiment	X-ray (resolution=2.75, R-factor=0.215)
reference complex	6w64_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7d2l_A interface=6,161,162,164,165,168,228,230,292,309,312,475,476,623,644,753,882,883,890,894,897,898,901,926,927,928,960, nasetRkayttkmiprshdrmkllgnfmdylmdgtpiffelwnqfgggidrdiisgtankdkisddlllavnwfkvmpinskpqgvspsnlanlfqqysgsepdiqaqeyfasnfdtekhqwkdmrveyerllaelqlsrsdmhhdlklmykekciglslSTaHYitSvmfgtgaknnrqtkhqfyskviqlleestqinsveqlasiilkagdcdsyrklrircsrKgAtpsilkivqdyelgtnhddevnvpslianlkeklgrfeyecewkcmekikaflaskvgpyyLgsysamlenalspikgMttKnckfvlkqidakndikyenepfgkivegffdspyfesdtnvkwvlhphhigesniktlwedlnaihskyeediaslsedkkekrikvyqgdvcqtintyceevgkeaktplvqllrylysrkddiavdkiidgitflskkhkvekqkinpviqkypsfnfgnNSkllgkiispkdklkhnlkcnrnqvdnyiwieikvlntktmrwekhhyalsstrfleevyypatsenppdalaarfrtktngyegkpalsaeqieqirsapvglrkvkkrqmrleaarqqnllprytwgkdfninickrgnnfevtlAtkvkkkkeknykvvlgyaanIvrkntyaaieahangdgvidyndlpvkpiesgfvtvesqvrdksydqlsyngvkllyckphvesrrsflekyrngtmkdnrgnniqidfmkdfeaiaddetslyyfnmKyckllqssirnhssqakeyreeifellrdgklsvlklsslsnlsfvmfkvaksligtyfghllkkpappitdedkqkadpemfalrlaleekrlnkvkskkeviankivakalelrdkygpvlikgenISdttkkgKkssTnsFLmdWlargvankvkemvmmhqglefvevNPNftshqdpfvhknpentfrarysrctpselteKnrkeilsflsdkpskrptnayynegamaflatyglkkndvlgvslekfkqimanilhqrsedqllfpsrggmfylatykldadatsvnwngkqfwvcnadlvaaynvglvdiqkdfk
interface signature	RSTHYSKALMKNSAIKISKTFLWNPNK

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5

specificity:

A |  54  13   0   0   0
C |  13  16   0   0  96
G |  16  54   0   0   0
T |  13  13  96  96   0

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updated Fri Jan 9 12:20:47 2026