7d2l_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE CAS12I1 R-LOOP COMPLEX BEFORE TARGET DNA CLEAVAGE (12I1-D647A)
reference	OuYang et al. 'Nat 12 3476 2021
source	LACHNOSPIRACEAE BACTERIUM ND2006
experiment	X-ray (resolution=2.75, R-factor=0.215)
reference complex	7eu9_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7d2l_A interface=161,162,164,165,168,228,230,292,475,476, nasetrkayttkmiprshdrmkllgnfmdylmdgtpiffelwnqfgggidrdiisgtankdkisddlllavnwfkvmpinskpqgvspsnlanlfqqysgsepdiqaqeyfasnfdtekhqwkdmrveyerllaelqlsrsdmhhdlklmykekciglslSTaHYitSvmfgtgaknnrqtkhqfyskviqlleestqinsveqlasiilkagdcdsyrklrircsrKgAtpsilkivqdyelgtnhddevnvpslianlkeklgrfeyecewkcmekikaflaskvgpyyLgsysamlenalspikgmttknckfvlkqidakndikyenepfgkivegffdspyfesdtnvkwvlhphhigesniktlwedlnaihskyeediaslsedkkekrikvyqgdvcqtintyceevgkeaktplvqllrylysrkddiavdkiidgitflskkhkvekqkinpviqkypsfnfgnNSkllgkiispkdklkhnlkcnrnqvdnyiwieikvlntktmrwekhhyalsstrfleevyypatsenppdalaarfrtktngyegkpalsaeqieqirsapvglrkvkkrqmrleaarqqnllprytwgkdfninickrgnnfevtlatkvkkkkeknykvvlgyaanivrkntyaaieahangdgvidyndlpvkpiesgfvtvesqvrdksydqlsyngvkllyckphvesrrsflekyrngtmkdnrgnniqidfmkdfeaiaddetslyyfnmkyckllqssirnhssqakeyreeifellrdgklsvlklsslsnlsfvmfkvaksligtyfghllkkpappitdedkqkadpemfalrlaleekrlnkvkskkeviankivakalelrdkygpvlikgenisdttkkgkksstnsflmdwlargvankvkemvmmhqglefvevnpnftshqdpfvhknpentfrarysrctpselteknrkeilsflsdkpskrptnayynegamaflatyglkkndvlgvslekfkqimanilhqrsedqllfpsrggmfylatykldadatsvnwngkqfwvcnadlvaaynvglvdiqkdfk
interface signature	STHYSKALNS

Estimated binding specificities ?

readout + contact

# IC=4.434 IC/col=0.887 n_of_columns=5

specificity:

A |  54  16   0   0   0
C |  16  13   0   0  96
G |  13  54   0   0   0
T |  13  13  96  96   0

scan!

home
updated Tue Dec 17 08:56:55 2024