7dbn_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE MUTANT Q151M/Y115F/F116Y/M184V/F160M:DNA:DCTP TERNARY COMPLEX
reference	Hattori et al. J.Virol. 95 e0240120 2021
source	HUMAN IMMUNODEFICIENCY VIRUS 1 / HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
experiment	X-ray (resolution=2.67, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7dbn_C interface=24,61,74,76,78,94,151,157,183,265,448,475,501, pispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdafysvpldkdfrkytaftipsinnetpgiryqynvlpMgwkgsPaimqssmtkilepfrkqnpdiviyqYvddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 7dbn_D interface= ietvpvklkpgmdgpkvkqwpltEekikalveictemekegkiskigpenpyntpvfaikKkdstkwrklvdfReLnKrtqdfwevqlgiphpAglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkGspaifQssmtkilepfrkqnpdiviyqymddLyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgTkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFLDRIMPYNRQY/EKRLKAGQLT

Estimated binding specificities ?

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# IC=7.580 IC/col=0.237 n_of_columns=32

specificity:

A |   0   0  24   0  24   7  24  24  24  24  24  24  24  24  24   7  24  24   7  24  24  24  24  24  24  24  24  24  24  24   9   0
C |   0   0  24  96  24  73  24  24  24  24  24  24  24  24  24   9  24  24   7  24  24  24  24  24  24  24  24  24  24  24   7   0
G |   0  96  24   0  24   9  24  24  24  24  24  24  24  24  24   7  24  24  73  24  24  24  24  24  24  24  24  24  24  24  73  96
T |  96   0  24   0  24   7  24  24  24  24  24  24  24  24  24  73  24  24   9  24  24  24  24  24  24  24  24  24  24  24   7   0

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updated Tue Jan 6 22:12:50 2026