7ea8_A : 3D-footprint complex

Interface of input file ?

3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.

Dendrogram of similar interfaces ?

matrix format

structure name	HUMAN SETD2 BOUND TO A NUCLEOSOME CONTAINING ONCOHISTONE MUTATIONS
experiment	NMR
structural superfamily	Histone-fold;
sequence family	Core histone H2A/H2B/H3/H4;
multimeric complexes	7ea8_ABCDEFGH
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7ea8_A interface=8,51, ggvmkphRyrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlRfqsaaigalqeaseaylvglfedtnlcaihakrvtimpkdiqlarrirge

  
  --RG--------RG------                     +--------------6iy2_A    
                                 +--------10  
  --RG--------RT------           !         !              +7zs9_e    
                                 !         +--------------1 
  --RG--------RT------           !                        +8grq_A    
                                 !  
  --RG----------------           !     +--------------------5z3u_A    
                                 !  +-17  
  --RT----LA--RG------           !  !  !    +---------------7unc_a    
                                 !  !  +---11  
  HARA----LT--RC------       +--21  !       !              +3kwq_E    
                             !   !  !       +--------------3 
  --RG----LC--RT------       !   !  !                      +8hr1_E    
                             !   !  !  
  --RT--RG------------       !   !  !     +--------------------6pww_K    
                             !   !  !     !  
  HARAYT--LT--RC------       !   !  !     !  +-------------------4xzq_E    
                             !   !  !     !  !  
  --RCYA------RG------       !   !  !  +-18  !              +---------7ccr_A    
                             !   +-20  !  !  !     +--------9 
  ------------RG------       !      !  !  !  !     !        +---------8ox0_C    
                             !      !  !  !  !     !  
  --------LT----------       !      !  !  !  !     !             +------7ywx_E    
                             !      !  !  +-16  +-14  +----------8 
  ------------RG------       !      !  !     !  !  !  !          +------5x0y_G    
                             !      !  !     !  !  !  !  
  ------------RC------       !      !  !     !  !  !  !                  +7xyf_B    
                           -22      !  !     !  !  !  !                +-5 
  ----------------KG--       !      !  !     !  !  +-13           +----6 +7nkx_f    
                             !      !  !     !  !     !           !    ! 
  ------------RG------       !      +-19     !  !     !  +--------7    +-8jla_C    
                             !         !     +-15     !  !        ! 
  ------------RA------       !         !        !     !  !        !     +1zla_C    
                             !         !        !     +-12        +-----4 
  ------------RA----RA       !         !        !        !              +6a5l_g    
                             !         !        !        !  
  ----------IT--------       !         !        !        !               +3wkj_D    
                             !         !        !        +---------------2 
  --------------RA----       !         !        !                        +6g0l_D    
                             !         !        !  
  --------EA----RG----       !         !        +------------------7n8n_A    
                             !         !  
  HGRGYG--QC--RG------       !         +---------------------7y7i_E    
                             !  
  ------------RT------       +----------------------------7kbd_C

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updated Sun Aug 3 16:14:54 2025