7jtn_A : 3D-footprint complex

structure name	HUMAN COMPLEMENT FACTOR B INHIBITED BY A SLOW OFF-RATE MODIFIED APTAMER OF 29 BASES (COMPLEMENT FACTOR B)
reference	Geisbrecht et al. 'J 206 861 2021
source	HOMO SAPIENS
experiment	X-ray (resolution=3.10, R-factor=0.210)
structural superfamily	Trypsin-like serine proteases;vWA-like;Complement control module/SCR domain;
sequence family	Trypsin; von Willebrand factor type A domain; Sushi domain SCR repeat;
redundant complexes	7jtq_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7jtn_A interface=38,39,40,44,185, qgscslegveikggsfrllqegqaleyvcpsgfypypVQTrtcRstgswstlktktvrkaecraihcprphdfengeywprspyynvsdeisfhcydgytlrgsanrtcqvngrwsgqtaicdngagycsnpgipigtrkvgsqyrledsvtyhcsrgltlrgsqrrtcqeggswsgtepscqdSfmydtpqevaeaflssltetikrkivldpsgsmniylvldgsdsigasnftgakkclvnliekvasygvkpryglvtyatypkiwvkvseadssnadwvtkqlneinyegtntkkalqavysmmswpddvppegwnrtrhviilmtdglhnmggdpitvideirdllyigkdrknpredyldvyvfgvgplvnqvninalaskkdneqhvfkvkdmenledvfyqmidesqslslcgmvwehrkgtdyhkqpwqakisvirpskghescmgavvseyfvltaahcftvddkehsikvsvggekrdleievvlfhpnyningkkeagipefydydvaliklknklkygqtirpiclpctegttralrlpptttcqqqkeellpaqdikalfvseeekkltrkevyikngdkkgscerdaqyapgydkvkdisevvtprflctggvspyadpntcrgdsggplivhkrsrfiqvgviswgvvdvcknqvpahardfhinlfqvlpwlkeklqdedlgfl

No structural evidence for specific binding to DNA (<4 informative columns)

Dendrogram of similar interfaces ?

matrix format

  
  VAQATARGSA------------------------------------               +--------------------7jtn_A    
                                                          +----1 
  ------------------------------------------ITIT   L   +--2    +--------------------6z8v_H    
                                                       !  ! 
  ------------RGFTQCPGQCRCSTRANAFTVTNCLCKTLT----   L --3  +-------------------------3hxo_A    
                                                       ! 
  ----------KT----------------------------------       +----------------------------1jey_B

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updated Tue Dec 19 18:25:31 2023