7lrm_AB : 3D-footprint complex

structure name	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DNA, DCTP, AND CA(2+) ION
reference	Ruiz et al. 'Drug 27 1832 2022
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
experiment	X-ray (resolution=3.14, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7lrm_A interface=61,74,94,115,151,157,183,184,265,448,475,501, pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkLvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpQgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtnsqYalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvs > 7lrm_B interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaiKkkdstkwrklvdFrelnkrtqdfwevqlgiphPaglkkkksvtvldvgdayfsVpldedfrkytaftipsinnetpgiryqynvlpqgwKgspaiFqssmtkilepfkkqnpdiviyqymdDLyvgsdleigqhrtkieelrqhllrwgltpflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrQlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	FLIYQPYMNRQY/KFPVKFDLQ

Estimated binding specificities ?

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# IC=8.936 IC/col=0.279 n_of_columns=32

specificity:

A |   0  16   0  24  16  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24   8   0   0
C |   0  48  96  24  56  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24   8   0   0
G |  96  16   0  24   8  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  72  96  96
T |   0  16   0  24  16  24  24  24  24  24  24  24  24  24  96  24  96  24  24  24  24  24  24  24  24  24  24  24  24   8   0   0

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updated Wed Jan 7 02:19:00 2026