structure nameHUMAN DNA POL ETA S113A WITH RA-ENDED PRIMER AND DAMPNPP
(DNA polymerase eta)
referenceGregory et al. Proc.Natl.Acad.Sci.USA 118 ? 2021
sourceHomo sapiens
experimentX-ray (resolution=1.81, R-factor=0.186)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQWIRSSNPTL

Estimated binding specificities ?

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# IC=4.367 IC/col=0.873 n_of_columns=5 specificity:   
A |  96   0   0  21  10
C |   0   0   0  23  10
G |   0   0   0  10  21
T |   0  96  96  42  55
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updated Sat Aug 2 17:06:25 2025