interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POL ETA S113A WITH DT-ENDED PRIMER AND 0.1 MM DAMPNPP
(DNA polymerase eta)
referenceGregory et al. Proc.Natl.Acad.Sci.USA 118 ? 2021
sourceHomo sapiens
experimentX-ray (resolution=1.85, R-factor=0.184)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNLRF

Estimated binding specificities ?

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# IC=1.798 IC/col=0.300 n_of_columns=6 specificity:   
A |  74  19  25  24  12   4
C |   7  19  22  24  60   4
G |   7  20  27  24  12  84
T |   8  38  22  24  12   4
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updated Sat Aug 2 17:06:27 2025