7mca_ABCDEFI : 3D-footprint complex

structure name	STRUCTURE OF THE S. CEREVISIAE ORIGIN RECOGNITION COMPLEX BOUND TO THE REPLICATION INITIATOR CDC6 AND THE ARS1 ORIGIN DNA.
source	SACCHAROMYCES CEREVISIAE
experiment	NMR
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;Inhibitor of apoptosis IAP repeat;"Winged helix" DNA-binding domain;
reference complex	5v8f_B 5v8f_C 5v8f_D 5v8f_E 5zr1_A 5zr1_F 7mca_I
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7mca_A interface=6,8,13,18, pvirkFtKknvaRakkkYtpfskrfksiaaipdltslpefygnsselmasrfenklkttqkhqivetifskvkkqlnssylparenefasiylsaysaiesdsattiyvagtpgvgktltvrevvkellsssaqreipdflyveinglkmvkptdcyetlwnkvsgerltwaasmeslefyfkrvpknkkktivvlldeldamvtksqdimynffnwttyenakliviavantmdlperqlgnkitsrigftrimftgytheelkniidlrlkglndsffyvdtktgnailidvrkvrlrmsadaieiasrkvasvsgdarralkvckraaeiaekhymakhgygydgvqtvhithvmkalnetlnshvitfmtrlsftaklfiyallnlmkkngsqeqelgdivdeikllievngsnkfvmeiaktlfqqgsdniseqlriiswdfvlnqlldagilfkqtmkndriccvklnisveeakramnedetlrnl > 7mca_B interface=22,152, tksassfldtfegyfdqrkivRtnaksrhtmsmapdvtreefslvsnffnenfqkrprqklfeiqkkmfpqywfeltqgfsllfygvgskrnfleefaidylspkiaysqlnsipclilngynpscnyrdvfkeitdllvpaeltrsetkyWgnhvilqiqkmidfyknqpldiklilvvhnldgpsirkntfqtmlsflsvirqiaivastdhiyapllwdnmkaqnynfvfhdisnfepstvestfqdvmk > 7mca_C interface= fadaqrshytvypslpqsnknDkhipfvkllsgkesevnvekrwelyhqlhshfhdqvdhiidnieadlkaeisdllysettqkrrcfntifllgsdsttkielkdessrynvlieltpkespnvrmmlrrsmyklysaadaeehnndvsyDlslvenfkrlfgkdlamvfnfkdvdsinfntldnfiillksafkydhvkislifnintnlsnieknlrqstirllkrnyhkldvssnkgfkygnqifqsfldtvdgklnlsdrfvefilskmanntnhnlqlltkmldyslmsyffqnafsvfidpvnvdflnddylkilsrcptfmffveglikqhapadeilslltnknrgleeffveflvrenpinghakfvarfleeelnitnfnlielyhnlligkldsyldrwsackeykdrlhfepidtifqelftldnrsglltqsifpsyksniednllsweqvlpsldkenydtlsgdldkimapvlgqlfklyreanmtiniydfyiafretlpkeeilnfirkdpsntkllelaetpdafdkvalilfmqaifafenmglikfqstksydlvekcvwrgi > 7mca_D interface=394,395,398,399, dpgfgslqrrllqqlygtlptdekiiftylqdcqqeidriikqsiiqkeshsvilvgprqsyktylldyelsllqqsykeqfitirlngfihseqtaingiatqleqqlqkihtissgsltevfekilllldssitkitvvfifdeidtfagpvrqtllynlfdmvehsrvpvcifgcttklnileylekrvksrfsqrviympqiqnlddmvdavrnlltvrseispwvsqwnetlekelsdprsnlnrhirmnfetfrslptlknsiiplvatsknfgslctaikscsfldiynknqlsnnltgrlqslsdlelailisaarvalrakdgsfnfnlayaeyekmikainsrintiklwlkkdvknvwenlvqldffteksavglrdnataaFYasNYqfqgtmipfdlrsyqmqiilqelrriipksnmyyswtql > 7mca_E interface=326,342,345,348,413, mnvttpevafreyqtnclasyisadpditpsnlilqgysgtgktytlkkyfnanpnlhavwlepvelvswkpllqaiartvqyklktlypnipttdydplqveepfllvktlhnifvqyeslqektclflildgfdslqdldaalfnkyiklnellpkdskinikfiytmletsflqrysthciptvmfprynvdevstilvmsrcgelmedsclrkriieeqitdctddqfqnvaanfihlivqafhsytgndifalndlidfkwpkyvsritkenifeplalyksaiklflstddnlssqtydlsiiskylliasyicsylepRydasifsrktriiqgRaaYgrRkkkevnprylqpslfaierllaifqaifpiqgalreeslmkanievfqnlselhtlkliattmnKnidylspkvrwkvnvpweiikeisesvhfnisdyfsdih > 7mca_F interface=10,11, ripnsllvkKYckmtteeiirlcndfelprevaykivdeyninasrlvcpwqlvcglvlnctfivfnerrrkdpridhfivskmcslmltskvddviecvklvkeliigekwfrdlqiryddfdgirydeiifrklgsmlqttnilvtddqyniwkkriemdla > 7mca_I interface= allqksselVNlnartaeyeqvmnflakaisehrsdslyitgppgtgktaqldmiirqkfqslesvavtsincislgepssifqkifdsfqdlngptlqiknmqhlqkflepyhkkttfvvvldemdrllhantsetqsvrtilelfllaklptvsfvligmansldmkdrflsrlnldrgllpqtivfqpytaeqmyeiviqkmsslptiifqpmaikfaakkcagntgdlrklfdvlrgsieiyelekgkiglnyiakvfskfvnnnstrtriaklniqqklilctiiqslklnsdatidesfdhyikaitkaplqrnefleictiletcglvsikktkckgktkrfvdkidvdldmrefydemtkisilkpfl
interface signature	FKRY/RW/DD/FYNY/RRYRK/KY/VN

Estimated binding specificities ?

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# IC=21.976 IC/col=0.733 n_of_columns=30

specificity:

A |   4   0   1  93   1   1   1   5   1  74   0  94  24   1  24  24  24  24  24  24  24  24  24   1   6   0   1   0   0   0
C |   1   0   1   1   1   1   7   7   1   7   0   1  24  94  24  24  24  24  24  24  24  24  24   0   9  96   1   0   0   0
G |   1   0   4   1   4  90   9   7   4   8  96   1  24   1  24  24  24  24  24  24  24  24  24   1  74   0   1   0   0   0
T |  90  96  90   1  90   4  79  77  90   7   0   0  24   0  24  24  24  24  24  24  24  24  24  94   7   0  93  96  96  96

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updated Wed Jan 7 03:19:44 2026