structure nameRNA POLYMERASE II PRE-INITIATION COMPLEX (PIC2)
sourceSACCHAROMYCES CEREVISIAE
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;
reference complex5oqj_M 5oqj_Q 5oqj_R 5oqj_U 5oqj_X 7ml0_W
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDRR/KS/NVFLTNVFLVT/RVLVQNKLLSK/VRV/LKDLIVQQLLE/AEEGEESEADG

Estimated binding specificities ?

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# IC=12.380 IC/col=0.344 n_of_columns=36 specificity:   
A |   0   0  84   4  78  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   6   0  24  96   0  82   5  82
C |   0   0   4  82   4  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4   0  24   0   0   4   0   6
G |  96   0   4   6  10  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4   0  24   0   0   4   4   4
T |   0  96   4   4   4  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  82  96  24   0  96   6  87   4
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updated Wed Jan 7 04:14:38 2026