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structure nameZBTB7A ZINC FINGER DOMAIN BOUND TO -200 SITE OF FETAL GLOBIN PROMOTER (OLIGO 6)
(Zinc finger and BTB domain-containing protein 7A)
referenceHorton et al. 'Cell 36 109759 2021
sourceHomo sapiens
experimentX-ray (resolution=2.86, R-factor=0.228)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
multimeric complexes7n5v_AB
redundant complexes7n5t
reference complex8h9h_G
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRRDKRSDHR

Estimated binding specificities ?

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# IC=6.065 IC/col=0.607 n_of_columns=10 specificity:   
A |   3   3   6   6  35  25   6   4   1   6
C |   3   6   6   6  20  24   6   4   0   6
G |  87  67  78  78  22  24  64  84  95  76
T |   3  20   6   6  19  23  20   4   0   8
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Dendrogram of similar interfaces ?

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updated Sun Jun 28 23:23:00 2026