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structure nameZBTB7A ZINC FINGER DOMAIN BOUND TO -200 SITE OF FETAL GLOBIN PROMOTER (OLIGO 6)
(Zinc finger and BTB domain-containing protein 7A)
referenceHorton et al. 'Cell 36 109759 2021
sourceHomo sapiens
experimentX-ray (resolution=2.86, R-factor=0.228)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
multimeric complexes7n5v_AB
redundant complexes7n5t
reference complex8h9h_G
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRRDKRSDHR

Estimated binding specificities ?

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# IC=5.941 IC/col=0.594 n_of_columns=10 specificity:   
A |   7   0   3  18  23  20   6   7  19   3
C |  77  95  84  65  24  20  76  77  66  86
G |   6   1   5   7  24  21   8   6   5   3
T |   6   0   4   6  25  35   6   6   6   4
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Dendrogram of similar interfaces ?

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updated Fri Jan  9 13:57:55 2026