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structure nameZBTB7A ZINC FINGER DOMAIN BOUND TO -200 SITE OF FETAL GLOBIN PROMOTER (OLIGO 6)
(Zinc finger and BTB domain-containing protein 7A)
referenceHorton et al. 'Cell 36 109759 2021
sourceHomo sapiens
experimentX-ray (resolution=2.86, R-factor=0.228)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
multimeric complexes7n5v_AB
redundant complexes7n5t
reference complex7n5w_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRRDKRSDHR

Estimated binding specificities ?

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# IC=5.949 IC/col=0.595 n_of_columns=10 specificity:   
A |   7   0   3  19  23  20   6   7  17   3
C |  77  95  84  65  23  21  75  77  68  86
G |   6   1   5   6  25  21   8   6   5   3
T |   6   0   4   6  25  34   7   6   6   4
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Dendrogram of similar interfaces ?

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updated Fri Sep 13 04:56:31 2024