7oxq_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE WITH A DOUBLE STRANDED DNA IN COMPLEX WITH FRAGMENT 048 AT THE TRANSIENT P-POCKET.
reference	Martinez et al. 'Nat 12 7127 2021
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 BH10
experiment	X-ray (resolution=3.30, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7oxq_A interface=73,75,95,116,152,158,184,185,266,449,476, vpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfackkkdstkwRkLvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpQgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 7oxq_B interface= ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdFrElnkrtqdfwphpaglkkkkSvtvldvgdayfsvpldedfrKytaftipsinnetpgiryqynvlpqgwkgspaifqSsmtkiLepfkkqnpdiviyqymddlyvgsdlEIgqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikVrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	RLIYQPYMNRQ/FESKSLEIV

Estimated binding specificities ?

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# IC=2.744 IC/col=0.144 n_of_columns=19

specificity:

A |  38  13  24  21  24  24  24  24  24  24  24  24  25  24  20  13  10  12   0
C |  20  14  24  31  24  24  24  24  24  24  24  24  22  24  36  13  70  60   0
G |  19  56  24  21  24  24  24  24  24  24  24  24  27  24  20  57   8  12  96
T |  19  13  24  23  24  24  24  24  24  24  24  24  22  24  20  13   8  12   0

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updated Fri Jun 26 17:19:33 2026