7oxq_CD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE WITH A DOUBLE STRANDED DNA IN COMPLEX WITH FRAGMENT 048 AT THE TRANSIENT P-POCKET.
reference	Martinez et al. 'Nat 12 7127 2021
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 BH10
experiment	X-ray (resolution=3.30, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7oxq_C interface=91,180,445,472, pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfackkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqYmddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 7oxq_D interface= ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiPhpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqyMddlyvgsdleigqhrtkieelrqhllrwglwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYRQ/PM

Estimated binding specificities ?

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# IC=3.968 IC/col=0.233 n_of_columns=17

specificity:

A |   9   0  24  11  24  24  24  24  24  24  24  24  24  24  24   9   0
C |   9  96  24  67  24  24  24  24  24  24  24  24  24  24  24  67   0
G |  11   0  24   9  24  24  24  24  24  24  24  24  24  24  24  11  96
T |  67   0  24   9  24  24  24  24  24  24  24  24  24  24  24   9   0

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updated Wed Jan 7 07:32:13 2026