7oz2_CD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE WITH A DOUBLE STRANDED DNA SHOWING A TRANSIENT P-POCKET
reference	Martinez et al. 'Nat 12 7127 2021
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 BH10
experiment	X-ray (resolution=2.85, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7oz2_C interface=91,180,445,472, pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfackkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqYmddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 7oz2_D interface= ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiPhpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqyMddlyvgsdleigqhrtkieelrqhllrwglwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYRQ/PM

Estimated binding specificities ?

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# IC=4.518 IC/col=0.266 n_of_columns=17

specificity:

A |   1   0  15  15  24  24  24  24  24  24  24  24  24  24  24   6   5
C |   5  96  61  55  24  24  24  24  24  24  24  24  24  24  24  80   5
G |   0   0   5  10  24  24  24  24  24  24  24  24  24  24  24   5  81
T |  90   0  15  16  24  24  24  24  24  24  24  24  24  24  24   5   5

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updated Wed Jan 7 07:33:44 2026