7oz5_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE WITH A DOUBLE STRANDED DNA IN COMPLEX WITH FRAGMENT 166 AT THE TRANSIENT P-POCKET.
reference	Martinez et al. 'Nat 12 7127 2021
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 BH10
experiment	X-ray (resolution=3.37, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7oz5_A interface=67,73,75,95,116,152,158,184,185,449,476, vpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfackkKdstkwRkLvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpQgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 7oz5_B interface= ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkWrklvdFrElnkrtqdfwphpaglkkkkSvtvldvgdayfsvpldedfrKytaftipsinnetpgiryqynvlpqgwkgspaifqSsmtkiLepfkkqnpdiviyqymddlyvgsdlEIgqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	KRLIYQPYMRQ/WFESKSLEI

Estimated binding specificities ?

contact

# IC=7.140 IC/col=0.376 n_of_columns=19

specificity:

A |   0   0   0   0  16  24  24  24  24  24  24  24  24  24  24  24  24   0  13
C |  96   0   0  96  13  24  24  24  24  24  24  24  24  24  24  24  24  96  13
G |   0  96  96   0  54  24  24  24  24  24  24  24  24  24  24  24  24   0  13
T |   0   0   0   0  13  24  24  24  24  24  24  24  24  24  24  24  24   0  57

scan!

home
updated Wed Jan 7 07:37:12 2026