7oz5_CD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE WITH A DOUBLE STRANDED DNA IN COMPLEX WITH FRAGMENT 166 AT THE TRANSIENT P-POCKET.
reference	Martinez et al. 'Nat 12 7127 2021
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 BH10
experiment	X-ray (resolution=3.37, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7oz5_C interface=91,180,445,472, pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfackkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqYmddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 7oz5_D interface= ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiPhpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqyMddlyvgsdleigqhrtkieelrqhllrwglwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYRQ/PM

Estimated binding specificities ?

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# IC=3.882 IC/col=0.228 n_of_columns=17

specificity:

A |   7   0  24  24  24  24  24  24  24  24  24  24  24  24   0   0  73
C |  75   7  24  24  24  24  24  24  24  24  24  24  24  24  14   0   7
G |   7  81  24  24  24  24  24  24  24  24  24  24  24  24  68  96   9
T |   7   8  24  24  24  24  24  24  24  24  24  24  24  24  14   0   7

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updated Wed Jan 7 07:36:30 2026