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structure nameTHE CRYSTAL STRUCTURE OF THE L439V VARIANT OF POL2CORE IN COMPLEX WITH DNA AND AN INCOMING NUCLEOTIDE
(DNA polymerase epsilon catalytic subunit A)
referenceShcherbakova et al. 'Nucleic 50 8023 2022
sourceSaccharomyces cerevisiae
experimentX-ray (resolution=2.46, R-factor=0.212)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family B, exonuclease do; DNA polymerase family B 933;
reference complex4m8o_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKR

Estimated binding specificities ?

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# IC=2.340 IC/col=0.585 n_of_columns=4 specificity:   
A |   7   7   7   7
C |  73   7   9   7
G |   7  75   7   7
T |   9   7  73  75
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updated Fri Sep 13 07:25:27 2024