7s03_A : 3D-footprint complex

structure name	DNA-BINDING DOMAIN OF HUMAN SETMAR IN COMPLEX WITH HSMAR1 TERMINAL INVERTED REPEAT (TIR) DNA (Histone-lysine N-methyltransferase SETMAR)
reference	Georgiadis et al. J.Biol.Chem. 298 101894 2022
source	Homo sapiens
experiment	X-ray (resolution=2.37, R-factor=0.212)
structural superfamily	Homeodomain-like;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7s03_A interface=41,42,43,45,46,63,66,87,88,97,98,99,100,102,103, kmmldkkqiraiflfefkmgrkaaettrnmnnafgpgtanERTvQWwfkkfrkgdesledeeRsgRpsevdndqlraiieadplttTRevaeemnvNHSTvVRhlkqi
interface signature	ERTQWRRTRNHSTVR

Estimated binding specificities ?

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# IC=18.838 IC/col=0.942 n_of_columns=20

specificity:

A |   4   0   0   2   0   0  85  74  91  24  10   0  78  24   4   0   0   0   0   4
C |   6   0   0   0   0  96   4   8   3  24   8   2   2  24  10   0   0  96   0   6
G |   6  96  96   3  96   0   3   8   2  24  74   1   6  24  10   0  96   0  96  78
T |  80   0   0  91   0   0   4   6   0  24   4  93  10  24  72  96   0   0   0   8

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updated Sat Jan 10 17:22:25 2026