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3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.


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updated Sat Aug 2 20:32:38 2025
structure nameCRYSTAL STRUCTURE OF LIGASE I WITH NICK DUPLEXES CONTAINING MISMATCH A:C
(DNA ligase 1)
referenceCaglayan et al. 'Nat 13 3860 2022
sourceHomo sapiens
experimentX-ray (resolution=2.80, R-factor=0.177)
structural superfamilyATP-dependent DNA ligase DNA-binding domain;DNA ligase/mRNA capping enzyme, catalytic domain;Nucleic acid-binding proteins;
sequence familyATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal re;
reference complex8vdn_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence