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3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

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updated Fri Sep 13 07:45:07 2024

structure name	CRYSTAL STRUCTURE OF LIGASE I WITH NICK DUPLEXES CONTAINING COGNATE G:T (DNA ligase 1)
reference	Caglayan et al. 'Nat 13 3860 2022
source	Homo sapiens
experiment	X-ray (resolution=3.00, R-factor=0.206)
structural superfamily	ATP-dependent DNA ligase DNA-binding domain;DNA ligase/mRNA capping enzyme, catalytic domain;Nucleic acid-binding proteins;
sequence family	ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal re;
reference complex	8vdn_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7sxe_A interface=45,370,378,505,533,607, ldpsgynpaknnyhpvedacwkpgqkvpylavartfekieevsaRlrmvetlsnllrsvvalsppdllpvlylslnhlgppqqglalgvgdgvllkavaqatgrqlesvraeaaekgdvglvaensrmlppppltasgvfskfrdiarltgsastakkidiikglfvacrhsearfiarslsgrlrlglaeqsvlaalsqavsltppgqefppamvdagkgktaearktwleeqgmilkqtfcevpdldriipvllehglerlpehcklspgiplkpmlahptrgisevlkrfeeaaftceykydgqraqihaleggevkifsrnqadntgkypdiisripkiklpsvtsfildteavawdrekkqiqpFqvlttrkRkevdaseiqvqvclyafdliylngeslvreplsrrrqllrenfvetegefvfatsldtkdieqiaefleqsvkdsceglmvktldvdatyeiakrshnwlklkkdyldgvgdtldlvvigaylgrgKragryggfllasydedseelqaicklgTgfsdeeleehhqslkalvlpsprpyvridgavipdhwldpsavwevkcadlslspiypaarglvdsdkgislrFprfirvredkqpeqattsaqvaclyrkqsqi