7tjh_ABCDEI : 3D-footprint complex

structure name	S. CEREVISIAE ORC BOUND TO 84 BP ARS1 DNA AND CDC6 (STATE 1) WITH FLEXIBLE ORC6 N-TERMINAL DOMAIN
experiment	NMR
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;Inhibitor of apoptosis IAP repeat;"Winged helix" DNA-binding domain;
reference complex	5v8f_B 5v8f_C 5v8f_D 5v8f_E 5zr1_A 5zr1_F 7mca_I
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7tjh_A interface=5,7,12,17, virkFtKknvaRakkkYtpfskrfksiaaipdltslpefygnrfenklkttqkhqivetifskvkkqlnsslparenefasiylsaysaiesdsattiyvagtpgvgktltvrevvkellsssaqreipdflyveinglkmvkptdcyetlwnkvsgerltwaasmeslefyfkrvpknkkktivvlldeldamvtksqdimynffnwttyenakliviavantmdlperqlgnkitsrigftrimftgytheelkniidlrlkglndsffyvdtktgnailivrkvrlrmsadaieiasrkvasvsgdarralkvckraaeiaekhymakhgygydgvqtvhithvmkalnetlnshvitfmtrlsftaklfiyallnlmkkngsqeqelgdivdeikllievngsnkfvmeiaktlfqqgsdniseqlriiswdfvlnqlldagilfkqtmkndriccvklnisveeakramnedetlrnl > 7tjh_B interface=20,21,150, sassfldtfegyfdqrkivRTnaksrhtmsmapdvtreefslvsnffnenfqkrprqklfeiqkkmfpqywfeltqgfsllfygvgskrnfleefaidylspkiaysqlnsipclilngynpscnyrdvfkeitdllvpaeltrsetkyWgnhvilqiqkmidfyknqpldiklilvvhnldgpsirkntfqtmlsflsvirqiaivastdhiyapllwdnmkaqnynfvfhdisnfepstvestfqdvmk > 7tjh_C interface= adaqrshytvypslphipfVKllsgkesevnvekrwelyhqlhshfhdqvdhiidnieadlkaeisdllysrcfntifllgsdsttkielkdessrynvlieltpkespnvrmmlrrsmyklysaadaeendvsydlslvenfkrlfgkDlamvfnfkdvdsinfntldnfiillksafkydhvkislifnintnlsnieknlrqstirllkrnyhkldvssnkgfkygnqifqsfldtvdgklnlsdrfvefilskmanntnhnlqlltkmldyslmsyffqnafsvfidpvnvdflnddylkilsrcptfmffveglikqnrgleeffveflvrenpinghakfvarfleeelnitnfnlielyhnlligkldsyldrwsackeykdrlhfepidtifqelftldnrsglltqsifpsyksniednllsweqvlpslsgdldkimapvlgqlfklyreanmtiniydfyiafretlpkeeilnfirkdpsntkllelaetpdafdkvalilfmqaifafenmglikfqstksydlvekcvwrgi > 7tjh_D interface=390,391,394,395, dpgfgslqrrllqqlygtlptdekiiftylqdcqqeidriikqsiiqkeshsvilvgprqsyktylldyelsllqqsykeqfitirlngfihseqtaingiatqleqqlqkihtissgsltevfekillllditkitvvfifdeidtfagpvrqtllynlfdmvehsrvpvcifgcttklnileylekrvksrfsqrviympqiqnlddmvdavrnlltvrseispwvsqwnetlekelsdprsnlnrhirmnfetfrslptlknsiiplvatsknfgslctaikscsfldiynknqlsnnltgrlqslsdlelailisaarvalrakdgsfnfnlayaeyekmikainsrtiklwlkkdvknvwenlvqldffteksavglrdnataaFYasNYqfqgtmipfdlrsyqmqiilqelrriipksnmyyswtql > 7tjh_E interface=331,334,337, mnvttpevafreyqtnclasyisadpditpsnlilqgysgtgktytlkkyfnanpnlhavwlepvelvswkpllqaiartvqyklktlypnipttdydplqveepfllvktlhnifvqyeslqektclflildgfdslqdldaalfnkyiklnellpkdskinikfiytmletsflqrysthciptvmfprynvdevstilvmsrcgelmedsclrkriieeddqfqnvaanfihlivqafhsytgndifalndlidfkwpkyvsritkenifeplalyksaiklflstddnldlsiiskylliasyicsyleprydasifsrktriiqgRaaYgrRkkkevnprylqpslfaierllaifqaifpialreeslmkanievfqnlselhtlkliattmnknidylspkvrwkvnvpweiikeisesvhfnisdyfsdih > 7tjh_I interface= siflrtkallqksselgalpartaeyeqvmnflakaisehrsdslyitgppgtgktaqldmiirqkflqnlswfelpdgrlesvavtsincislgepssifqkifdsfqdlngptlqiknmqhlqkflepyttfvvvldemdrllhantsetqsvrtilelfllaklptvsfvligmansgllpqtivfqpytaeqmyeiviqkmsslptiifqpmaikfaakkcagntgdlrklfdvlrgsieiyelekkiglnyiakvfskfvnnnstrtriaklniqqklilctiiqslklnsdatidesfdhyikaitktdtlaplqrnefleictIleTcgLvsikktkckgktkrfvdkidvdldmrefydemtkisilkpfl
interface signature	FKRY/RTW/VKD/FYNY/RYR/ITL

Estimated binding specificities ?

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# IC=18.018 IC/col=0.601 n_of_columns=30

specificity:

A |   2   0   0  92   0   0   0  24  13  96   2  24  24  24  24  24  24  24  24  24  24  24  24   9   0   0   0   0   2  11
C |   2   0   4   0   3   0   4  24   9   0   0  24  24  24  24  24  24  24  24  24  24  24  24  16   0  96   2   0   4   2
G |   1   0   6   4   0  96   0  24   9   0  94  24  24  24  24  24  24  24  24  24  24  24  24  11   3   0   0   0  25   2
T |  91  96  86   0  93   0  92  24  65   0   0  24  24  24  24  24  24  24  24  24  24  24  24  60  93   0  94  96  65  81

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updated Wed Jan 7 10:40:22 2026