7tjh_ABCDEI : 3D-footprint complex

structure name	S. CEREVISIAE ORC BOUND TO 84 BP ARS1 DNA AND CDC6 (STATE 1) WITH FLEXIBLE ORC6 N-TERMINAL DOMAIN
experiment	NMR
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;Inhibitor of apoptosis IAP repeat;"Winged helix" DNA-binding domain;
reference complex	5v8f_B 5v8f_C 5v8f_D 5v8f_E 5zr1_A 5zr1_F 7mca_I
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7tjh_A interface=5,7,12,17, virkFtKknvaRakkkYtpfskrfksiaaipdltslpefygnrfenklkttqkhqivetifskvkkqlnsslparenefasiylsaysaiesdsattiyvagtpgvgktltvrevvkellsssaqreipdflyveinglkmvkptdcyetlwnkvsgerltwaasmeslefyfkrvpknkkktivvlldeldamvtksqdimynffnwttyenakliviavantmdlperqlgnkitsrigftrimftgytheelkniidlrlkglndsffyvdtktgnailivrkvrlrmsadaieiasrkvasvsgdarralkvckraaeiaekhymakhgygydgvqtvhithvmkalnetlnshvitfmtrlsftaklfiyallnlmkkngsqeqelgdivdeikllievngsnkfvmeiaktlfqqgsdniseqlriiswdfvlnqlldagilfkqtmkndriccvklnisveeakramnedetlrnl > 7tjh_B interface=20,21,150, sassfldtfegyfdqrkivRTnaksrhtmsmapdvtreefslvsnffnenfqkrprqklfeiqkkmfpqywfeltqgfsllfygvgskrnfleefaidylspkiaysqlnsipclilngynpscnyrdvfkeitdllvpaeltrsetkyWgnhvilqiqkmidfyknqpldiklilvvhnldgpsirkntfqtmlsflsvirqiaivastdhiyapllwdnmkaqnynfvfhdisnfepstvestfqdvmk > 7tjh_C interface= adaqrshytvypslphipfVKllsgkesevnvekrwelyhqlhshfhdqvdhiidnieadlkaeisdllysrcfntifllgsdsttkielkdessrynvlieltpkespnvrmmlrrsmyklysaadaeendvsydlslvenfkrlfgkDlamvfnfkdvdsinfntldnfiillksafkydhvkislifnintnlsnieknlrqstirllkrnyhkldvssnkgfkygnqifqsfldtvdgklnlsdrfvefilskmanntnhnlqlltkmldyslmsyffqnafsvfidpvnvdflnddylkilsrcptfmffveglikqnrgleeffveflvrenpinghakfvarfleeelnitnfnlielyhnlligkldsyldrwsackeykdrlhfepidtifqelftldnrsglltqsifpsyksniednllsweqvlpslsgdldkimapvlgqlfklyreanmtiniydfyiafretlpkeeilnfirkdpsntkllelaetpdafdkvalilfmqaifafenmglikfqstksydlvekcvwrgi > 7tjh_D interface=390,391,394,395, dpgfgslqrrllqqlygtlptdekiiftylqdcqqeidriikqsiiqkeshsvilvgprqsyktylldyelsllqqsykeqfitirlngfihseqtaingiatqleqqlqkihtissgsltevfekillllditkitvvfifdeidtfagpvrqtllynlfdmvehsrvpvcifgcttklnileylekrvksrfsqrviympqiqnlddmvdavrnlltvrseispwvsqwnetlekelsdprsnlnrhirmnfetfrslptlknsiiplvatsknfgslctaikscsfldiynknqlsnnltgrlqslsdlelailisaarvalrakdgsfnfnlayaeyekmikainsrtiklwlkkdvknvwenlvqldffteksavglrdnataaFYasNYqfqgtmipfdlrsyqmqiilqelrriipksnmyyswtql > 7tjh_E interface=331,334,337, mnvttpevafreyqtnclasyisadpditpsnlilqgysgtgktytlkkyfnanpnlhavwlepvelvswkpllqaiartvqyklktlypnipttdydplqveepfllvktlhnifvqyeslqektclflildgfdslqdldaalfnkyiklnellpkdskinikfiytmletsflqrysthciptvmfprynvdevstilvmsrcgelmedsclrkriieeddqfqnvaanfihlivqafhsytgndifalndlidfkwpkyvsritkenifeplalyksaiklflstddnldlsiiskylliasyicsyleprydasifsrktriiqgRaaYgrRkkkevnprylqpslfaierllaifqaifpialreeslmkanievfqnlselhtlkliattmnknidylspkvrwkvnvpweiikeisesvhfnisdyfsdih > 7tjh_I interface= siflrtkallqksselgalpartaeyeqvmnflakaisehrsdslyitgppgtgktaqldmiirqkflqnlswfelpdgrlesvavtsincislgepssifqkifdsfqdlngptlqiknmqhlqkflepyttfvvvldemdrllhantsetqsvrtilelfllaklptvsfvligmansgllpqtivfqpytaeqmyeiviqkmsslptiifqpmaikfaakkcagntgdlrklfdvlrgsieiyelekkiglnyiakvfskfvnnnstrtriaklniqqklilctiiqslklnsdatidesfdhyikaitktdtlaplqrnefleictIleTcgLvsikktkckgktkrfvdkidvdldmrefydemtkisilkpfl
interface signature	FKRY/RTW/VKD/FYNY/RYR/ITL

Estimated binding specificities ?

readout + contact

# IC=18.349 IC/col=0.612 n_of_columns=30

specificity:

A |  84  65  96  96   1  94  78  24  24  24  24  24  24  24  24  24  24  24  24   3   0  74  24  86   0  92   0  90  96  92
C |   3  27   0   0   4   1   5  24  24  24  24  24  24  24  24  24  24  24  24  91   0  10  24   0  96   2   3   1   0   0
G |   3   3   0   0  90   0   6  24  24  24  24  24  24  24  24  24  24  24  24   1   0   7  24   9   0   1   0   4   0   3
T |   6   1   0   0   1   1   7  24  24  24  24  24  24  24  24  24  24  24  24   1  96   5  24   1   0   1  93   1   0   1

scan!

home
updated Fri Jun 26 20:27:25 2026