interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ETA-DNA TERNARY MISMATCH COMPLEX:REACTION WITH 10.0 MM MN2+ FOR 600S
(DNA polymerase eta)
referenceChang et al. 'Nat 13 2346 2022
sourceHomo sapiens
experimentX-ray (resolution=1.67, R-factor=0.180)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSLRF

Estimated binding specificities ?

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# IC=1.598 IC/col=0.266 n_of_columns=6 specificity:   
A |   4  10  22  24  38  10
C |  81  10  22  24  19  10
G |   7  63  25  24  19  10
T |   4  13  27  24  20  66
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updated Fri Sep 13 08:03:39 2024