interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ETA-DNA TERNARY MISMATCH COMPLEX:REACTION WITH 1.0 MM MG2+ FOR 300S WITH FLIPPED-OUT PRODUCT
(DNA polymerase eta)
referenceChang et al. 'Nat 13 2346 2022
sourceHomo sapiens
experimentX-ray (resolution=1.47, R-factor=0.187)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQIRLSNR

Estimated binding specificities ?

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# IC=3.314 IC/col=0.473 n_of_columns=7 specificity:   
A |   0  92  21  24  24  13   7
C |   0   1  21  24  24  56   7
G |   0   1  23  24  24  13  74
T |  96   2  31  24  24  14   8
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updated Tue Dec 19 00:24:47 2023