interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ETA-DNA TERNARY MISMATCH COMPLEX:REACTION WITH 1.0 MM MG2+ FOR 300S WITH FLIPPED-OUT PRODUCT
(DNA polymerase eta)
referenceChang et al. 'Nat 13 2346 2022
sourceHomo sapiens
experimentX-ray (resolution=1.47, R-factor=0.187)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQIRLSNR

Estimated binding specificities ?

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# IC=3.314 IC/col=0.473 n_of_columns=7 specificity:   
A |   7  14  24  24  31   2   0
C |  74  13  24  24  21   1   0
G |   8  56  24  24  23   1  96
T |   7  13  24  24  21  92   0
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updated Fri Sep 13 08:03:45 2024