interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ETA-DNA-DGMPNPP TERNARY MISMATCH COMPLEX:NO ME2+ SOAKING
(DNA polymerase eta)
referenceChang et al. 'Nat 13 2346 2022
sourceHomo sapiens
experimentX-ray (resolution=1.64, R-factor=0.194)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSLRF

Estimated binding specificities ?

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# IC=3.184 IC/col=0.531 n_of_columns=6 specificity:   
A |  96  13  24  24  13   0
C |   0  13  24  24  57   0
G |   0  13  24  24  13  96
T |   0  57  24  24  13   0
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updated Mon Jun 29 03:33:58 2026