interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ETA-DNA-DGMPNPP TERNARY MISMATCH COMPLEX IN 0.12 MM MN2+ FOR 600S
(DNA polymerase eta)
referenceChang et al. 'Nat 13 2346 2022
sourceHomo sapiens
experimentX-ray (resolution=1.67, R-factor=0.189)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNLRF

Estimated binding specificities ?

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# IC=3.520 IC/col=0.587 n_of_columns=6 specificity:   
A |  96  20  24  24  19   0
C |   0  19  24  24  76   0
G |   0  19  24  24   1  96
T |   0  38  24  24   0   0
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updated Fri Sep 13 08:04:56 2024