7ugw_ABCD : 3D-footprint complex

structure name	M. TUBERCULOSIS DNA GYRASE CLEAVAGE CORE BOUND TO DNA AND EVYBACTIN
reference	Berger et al. Nat.Chem.Biol. ? ? 2022
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5bs8_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7ugw_A interface=17,25,77,114,167, iepvdieqemqrsyidYamsvivgRalpevrdglkpvhrrvlyamfdsgfrpdrshaksarsvaetmgnyhphgdaSiydslvrmaqpwslryplvdgqgnfgspgndppaamRftearltplamemlreideetvdfipnydgrvqeptvlpsrfpnllangsggIavgmatnipphnlreladavfwalenhdadeeetlaavmgrvkgpdfptaglivgsqgtadayktgrgsirmrgvveveergrtslvitelpyqvnhdnfitsiaeqvrdgklagisniedqssdrvglrivieikrdavakvvinnlykhtqlqtsfganmlaivdgvprtlrldqliryyvdhqldvivrrttyrlrkanerahilrglvkaldaldevialirasetvdiaraglielldideiqaqaildmqlrrlaalerqriiddlakieaeiadledilakperqrgivrdelaeivdrhgddrrtriiaa > 7ugw_B interface=55,57, elvrrkdigglpgkladcrstdprkselyvvegdsaggsaksgrdsmfqailplRgKiinvekaridrvlkntevqaiitalgtgihdefdigklryhkivlmadadvdgqhistllltllfrfmrplienghvflaqpplyklkwqrsdpefaysdrerdglleaglkagkkinkedgiqrykglgemdakelwettmdpsvrvlrqvtlddaaaadelfsilmgedvdarrsfitrnakdvrfldv > 7ugw_C interface=18,78,168, riepvdieqemqrsyidYamsvivgralpevrdglkpvhrrvlyamfdsgfrpdrshaksarsvaetmgnyhphgdaSiydslvrmaqpwslryplvdgqgnfgspgndppaamrftearltplamemlreideetvdfipnydgrvqeptvlpsrfpnllangsggIavgmatnipphnlreladavfwalenhdadeeetlaavmgrvkgpdfptaglivgsqgtadayktgrgsirmrgvveveedsrgrtslvitelpyqvnhdnfitsiaeqvrdgklagisniedqssdrvglrivieikrdavakvvinnlykhtqlqtsfganmlaivdgvprtlrldqliryyvdhqldvivrrttyrlrkanerahilrglvkaldaldevialirasetvdiaraglielldideiqaqaildmqlrrlaalerqriiddlakieaeiadledilakperqrgivrdelaeivdrhgddrrtriia > 7ugw_D interface=52,54, elvrrkglpgkladcrstdprkselyvvegdsaggsaksgrdsmfqailplRgKiinvekaridrvlkntevqaiitalgtgihdefdigklryhkivlmadadvdgqhistllltllfrfmrplienghvflaqpplyklkwdpefaysdrerdglleakedgiqrykglgemdakelwettmdpsvrvlrqvtlddaaaadelfsilmgedvdarrsfitrnakdvrfld
interface signature	YRSRI/RK/YSI/RK

Estimated binding specificities ?

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# IC=21.007 IC/col=0.457 n_of_columns=46

specificity:

A |   0  24  24  24  24  24  75   0   0  24  24  24  24  24  24  24  24  24   3   0  24  75   3   0  24  24   0   0   6  24   0   0  24  24  24  24  24  24  24  24  24   3   0  10  96   0
C |   0  24  24  24  24  24   6  96   0  24  24  24  24  24  24  24  24  24  87   0  24   9   5   0  24  24  96  96   9  24  96   0  24  24  24  24  24  24  24  24  24  87   0  10   0   0
G |  96  24  24  24  24  24   9   0  96  24  24  24  24  24  24  24  24  24   3  96  24   6  85  96  24  24   0   0   6  24   0  96  24  24  24  24  24  24  24  24  24   3  96  11   0  96
T |   0  24  24  24  24  24   6   0   0  24  24  24  24  24  24  24  24  24   3   0  24   6   3   0  24  24   0   0  75  24   0   0  24  24  24  24  24  24  24  24  24   3   0  65   0   0

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updated Wed Jan 7 11:42:07 2026