7w1m_ABDEH : 3D-footprint complex

Interface of input file ?

structure name	CRYO-EM STRUCTURE OF HUMAN COHESIN-CTCF-DNA COMPLEX
experiment	NMR
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;Smc hinge domain;ARM repeat;"Winged helix" DNA-binding domain;beta-beta-alpha zinc fingers;
reference complex	6wg3_A 6wg3_B 6wg3_D 6wg3_E 7w1m_C 7w1m_H
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7w1m_A interface= gflklieienfksykgrqiigpfqrftaiigpngsgksnlmdaisfvlgektsnlrvktlrdlihgapvgkpaanrafvsmvyseegaedrtfarvivggsseykinnkvvqlheyseeleklgilikarnflvfqgavesiamknpkertalfeeisrsgelaqeydkrkkemvkaeedtqfnyhrkkniaaerkeakqameklesvrdkfqetsdefeaarkrakkakqafeqikkerfdrfnacfesvatnideiykalsrnssaqaflgpenpeepyldginyncvapgkrfrpmdnlsggektvaalallfaihsykpapffvldeidaaldntnigkvanyikeqstcnfqaivislkeefytkaesligvypeqgdcviskvltfdltkypd > 7w1m_B interface= myikqviiqgfrsyrdqtivdpfsskhnvivgrngsgksnffyaiqfvlsdefshlrpeqrlallhegtgprvisafveiifdnsdnrlpidkeevslrrvigakkdqyfldkkmvtkndvmnllesagfsrsnpyyivkqgkinqmatapdsqrlkllrevagtrvyderkeesislmketegkrekinellkyieerlhtleeekeelaqyqkwdkmrraleytiynqelnetrakldelsakretsgeksrqlinhdtkelekmtnrqgmllkkkeecmkkirelgslpqeafekyqtlslkqlfrkleqcntelkkyshvnkkaldqfvnfseqkeklikrqeeldrgyksimelmnvlelrkyeaiqltfkqvsknfsevfqklvpggkatlvmkkgqftgvgirvsftgkqgemremqqlsggqkslvalalifaiqkcdpapfylfdeidqaldaqhrkavsdmimelavhaqfitttfrpellesadkfygvkfrnkvshidvitaemakdfveddtthg > 7w1m_D interface= tlfevvklgksamqsvvddwiesykqdrdialldlinffiqcsgcrgtvriemfrnmqnaeiirkmteefdedsgdypltmpgpqwkkfrsnfcefigvlirqcqysiiydeymmdtvislltglsdsqvrafrhtstlaamklmtalvnvalnlsihqdntqrqyeaernkmigkranerlelllqkrkelqenqdeienmmnsifkgifvhryrdaiaeiraicieeigvwmkmysdaflndsylkyvgwtlhdrqgevrlkclkalqslytnrelfpklelftnrfkdrivsmtldkeydvaveairlvtlilhgseealsnedcenvyhlvysahrpvavaageflhkklfsrhdpqaeealakrrgrnspngnlirmlvlffleselhehaaylvdslwessqellkdwecmtellleepvqgeeamsdrqesalielmvctirqaaeahppvgrgtgkrvltakerktqiddrnkltehfiitlpmllskysadaekvanllqipqyfdleiystgrmekhldallkqikfvvekhvesdvleacsktysilcseeytiqnrvdiarsqlidefvdrfnhsvedllqegeeaddddiynvlstlkrltsfhnahdltkwdlfgncyrllktgiehgampeqivvqalqcshysilwqlvkitdgspskedllvlrktvksflavcqqclsnvntpvkeqafmllcdllmifshqlmtggreglqplvfnpdtglqsellsfvmdhvfidqdeenqsmegdeedeankiealhkrrnllaafskliiydivdmhaaadifkhymkyyndygdiiketlsktrqidkiqcaktlilslqqlfnelvqeqgpnldrtsahvsgikelarrfaltfgldqiktreavatlhkdgiefafkyqnqkgqeypppnlaflevlsefsskllrqdkktvhsylekflteqmmerredvwlplisyrnsl > 7w1m_E interface= mmdsstfkrftasienildnledmlllgkhqlnelgsesakikamgimdklstdktvkvlnilekniqdgsklserlwrdlimervtksadaclttinimtspnmpkavyiedvierviqytkfhlqntlypqydpvyrqrvivmlynkvcdivsslselleiqlltdttilqvssmgitpffvenvselqlcaiklvtavfsryekhrqlileeiftslarlptskrslrnfrlpmyiqmvtalvlqliqcvvhlpdvvitnsyetamrtaqnflsiflkkcgskqgeedyrplfenfvqdllstvnkpewpaaelllsllgrllvhqfsnkstemalrvasldylgtvaarlrkdavtskmdeiqqlqkalldyldentetdpslvfsrkfyiaqwfrdttletekkeiettgqimhraenrkkflrsdtvdyddaclivrylasmrpfaqsfdiyltqilrvlgenaiavrtkamkclsevvavdpsilarldmqrgvhgrlmdnstsvreaavellgrfvlcrpqlaeqyydmlierildtgisvrkrvikilrdicieqptfpkitemcvkmirrvndeegikklvnetfqklwftptphndkeamtrkilnitdvvaacrdtgydwfeqllqnllkseedssykpvkkactqlvdnlvehilkyeensgrlvacittlflfskirpqlmvkhamtmqpylttkcstqndfmvicnvakilelvvplmehpsetflatieedlmkliikygmtvvqhcvsclgavvnkvtqnfkfvwacfnryygaisklksqhqedpnntslltnkpallrslftvgalcrhfdfdledfkgnskvnikdkvlellmyftkhsdeevqtkaiiglgfafiqhpslmfeqevknlynnilsdknssvnlkiqvlknlqtylqeedtrmqqadrdwkkvakqedlkemgdvssgmsssimqlylkqvleaffhtqssvrhfalnvialtlnqglihpvqcvpyliamgtdpepamrnkadqqlveidkkyagfihmkavagmkmsyqvqqainsalcshlysmirgnrqhrraflisllnlfddtaktdvtmllyiadnlacfpyqtqeeplfimhhiditlsvsgsnllqsfkesliefanvsqgillllmlkqhlknlcgfsdskiqkyspsesakvydkainrktgvhfhpkqtldflrsdmanskiteevkrsivkqyldfkllmehl > 7w1m_H interface=22,24,28,49,53,78,79,81,84,88,107,109,110,113,137,138,141,163,166,169,193,194,195,196,199,202,235,249,251,253,254,257,261,278,279,280,282,311, vsvydfeeetfqcelcsytcpRrSnldRhmkshtderphkchlcgrafRtvtLlrnhlnthtgtrphkcpdcdmafvTSgElvRhrrYkhthekpfkcsmcdyasvEvSKlkRhirshtgerpfqcslcsyasrdtYKlkRhmrthsgekpyecyicharftQsgTmkMhilqkhtenvakfhcphcdtviaRKSDlgVhlRkqhsyieqgkkcrycdavfheryaliqhqkshKnekrfkcdqcdyaCrQeRHmiMhkrThtgekpyacshcdktfRQKqLldmhfkryhdpnfvpaafvcskcgktftRrntmarhadnc
interface signature	////RSRRLTSERYESKRYKRQTMRKSDVRKCQRHMTRQKLR

Estimated binding specificities ?

readout + contact

# IC=17.523 IC/col=0.164 n_of_columns=107

specificity:

A |  24  22  24  24  69   6   2   4  14   0  20  30  19  24  24  24  24  24  12   0  72  16   6  88   4   8   0   6   1   0   0   2  18  31  22  22  23  60  17  20  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24
C |  24  20  24  24   9   6   1   7  52  96  36  22  38  24  24  24  24  24  60  96   8  14  78   2   4   7   0   6   1  96   0  88  18  21  25  22  21  12  15  20  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24
G |  24  20  24  24   9  78   1  81  16   0  20  22  20  24  24  24  24  24  12   0   8  52   6   4  81  74  96  78  92   0  96   2  18  21  27  22  31  12  49  34  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24
T |  24  34  24  24   9   6  92   4  14   0  20  22  19  24  24  24  24  24  12   0   8  14   6   2   7   7   0   6   2   0   0   4  42  23  22  30  21  12  15  22  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24

scan!

home
updated Wed Sep 11 15:45:10 2024