interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE NPAS4-ARNT2 HETERODIMER IN COMPLEX WITH DNA
referenceJing et al. 'to ? ? ?
experimentX-ray (resolution=4.27, R-factor=0.252)
structural superfamilyPYP-like sensor domain PAS domain;HLH, helix-loop-helix DNA-binding domain;
sequence familyPAS fold; Helixloophelix DNAbinding domain;
multimeric complexes7xi3_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHSIERR

Estimated binding specificities ?

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# IC=6.247 IC/col=0.781 n_of_columns=8 specificity:   
A |   0   0  73  24   9  96   7   9
C |   0  96   7  24   7   0  73  73
G |   0   0   9  24  73   0   7   7
T |  96   0   7  24   7   0   9   7
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updated Sat Jan 10 20:29:46 2026