7xn7_ABEW : 3D-footprint complex

structure name	RNA POLYMERASE II ELONGATION COMPLEX CONTAINING SPT4/5, ELF1, SPT6, SPN1 AND PAF1C
experiment	NMR
reference complex	7xn7_u
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7xn7_A interface=239,304,435,818,819,1338, sqfpyssaplrsvkevqfgllspeeiraisvvkieypeimdesrqrpregglndpklgsidrnfkcqtcgegmaecpghfghmelakpvfhigfipkikkvcecicmncgkllldetnptmaqairirdpkkrfnavwqlcktkmvceadapvsrggcgntqpvvrkdgmklwgtwkksrdaqperklltpgeilnvfkhispedcfrlgfnedyarpewmiitvlpvpppqvrpsiaMdettqgqddlthklsdilkaninvqklemdgspqhiineveqllqfhvatymdndiagqpqalqKsgrpvkairarlkgkegrlrgnlmgkrvdfsartvisgdpnleldqvgvpisiaktlsypetvtqynihrlteyvrngpnehpgakyvirdngdridlryhkragdivlqygwkverhlmdddpvlfnrqPslhkmsmmahrvkvmpystfrlnlsvtspynadfdgdemnlhvpqseetraelsqlcavplqivspqsnkpvmgivqdtlcgvrkmtlrdtfieyeqvmnmlfwvpswdgvvpqpailkpkplwtgkqllsiaipsgihlqrtdggnsllspkdngmlivdgkvmfgvvdkktvgsgggglihtvmrekgpkicaelfgniqkvvnywllhngfsigigdaiadastmkeithaissakeqvqeiiykaqhnelelkpgmtlresfegevsrtlndardsagrsaemnlkdlnnvkqmvsagskgsfiniaqmsacvgqqmvegkriafgfadrslphftkddfspeskgfvensylrgltpqefffhamagreglidtavkTAetgyiqrrlvkaledimvhydgttrnslgdiiqflygedgldgtqverqtidtipgsdkafhkryyvdlmdeknsikpdvieyaadilgdvelqkelnseyeqlvsdrkflreivfvngdhnwplpvnlrriiqnaqqifhldrakasdltipeiihgvrdlckklfvlrgenelikeaqqnatslfqclvrarlatrrileefrlnrdafewvlgtieaqfqrslvhpgemvgviaaqsigepatqmnvtlgvprlkeilnvakniktpaltvyldreialdiekakviqssieyttlknvtsateiyydpdptstvieedfdtveayfsqspwllrleldrarmldkqltmnqvadkisevfsddlfvmwsednadkliircrvieedqmlkrieahmldlialrgipgiskvymvkhkvsvpdesgeykneelwaletdginlaevmavpgvdssrtysnsfveilsvlgieatrsslykeilnviafdgsyvnyrhmallvdvmtsrgylmaitRhginradtgalmrcsfeetveilfeagaaaelddcrgvsenvmlgqlapmgtgafdvmidekllts > 7xn7_B interface=462, ddtittedcwtvisaffeekglvsqqldsfdefmetsiqdlvweeprlildqpaqhdninkryeirfgkiylsrptmteadgtthamfpqearlrnltysspvyldmeksmftsidgnkvhigkvpimlrskfcslrtldevdlykmkecpydmggyfvingsekvliaqersaanivqvfkkaapspishvaeirsalekgsrlistmqiklygredkgtgrtikatlpyvkqdipivivfralgvvpdgeilqhicydendwqmlemlkpcieegfviqdkevaldfigrrgsaalgirrekriqyakdilqkellphitqeegfetrktfflgymvnrlllcalerkdqddrdhfgkkrldlagpllanlfrilfrkltreiyrymqrcietdrdfnlnlavksttitsglkyslatgnwgeqkkamssragvsqvlnrytysstlshlrrtntpigrDgklakprqlhnthwglvcpaetpegqacglvknlsllsgisigspsepiinfleewgmepledydpaqhtkstrifvngvwtgihrdpsmlvstmrdlrrsgaispevsiirdirerefkiftdvgrvyrplfiveddeskdnkgelritkehirkiqqgydddvygwsslvtsgvieyvdgeeeetimiamtpedlqtndtakrikpemstsshhtfthceihpsmilgvaasiipfpdhnqsprntyqsamgkqamgvfltnynvrmdtmanilyypqkplaktqameylkfrelpagqnaivaiacysgynqedsmimnqssidrglfrslffrsymdqekrfgisiveefekptrattlrlkhgtyekldedgliapgvrvsgddiiigkttpippdteelgqrtkyhtkrdastplrstengivdqvllttnqeglkfvkvrmrttkvpqigdkfasrhgqkgtigvtyrhedmpfsaegivpdliinphaipsrmtvahliecllskvgsirgyegdatpftdltvdavsnllrdngyqsrgfevmynghtgkklmaqvffgptyyqrlrhmvddkiharargpvqvltrqpvegrsrdgglrfgemerdcmiahgaagflkerlmeasdafrvhvcgicglmsvianlkknqfecrscknktniyqlhipyaakllfqelmamniaprlytersg > 7xn7_E interface= ednnriisrlwrsfrtvkemaadrgyfisqeemdqsleefrskicdsmgnpqrklmsflanptpealekysdlgtlwvefcdepsvgiktmrnfclriqeknfstgifiyqnnitpsankmiptvspaiietfqesdlvvnithhelvpkhirlsdgeksqllqryklkesqlpriqredpvarylglkrgqvvkiirrsetsgryasyricl > 7xn7_W interface= pqrlliptvddpgiwgvkvrlgkekdvvrqilkkklaregtknpleiysafqrdsfkghvyiearkaeaindalkgnvnvfsnnskflvgiveykdllrpvkssdvkltrgsyvrvkngkfkgdlaqvdevlenglearlklvprldygfrpaqrlfseaearvheptirrdrdgfvtyggeeyyegflyktfrlqnlivnsinptlnelslfqsneesttidlstiadslketaknlvsfqpgdnveiingelnhltgtvssvnqstivsvrlhsdddtinsetveiptsdlrkifnvgdhvrvihgkhtddtglivevngdkvefisnqtkrtvivfsnylikstdstvsinesgrfelhdlvqvnsdlvgiviraqkdsfdvlcsdgkllslppvsiysklnlnpnqqiaidsngvevkvgdtvreftgerrqgtilhvyrnflflrsreivenqgvfVtssnrvktirdptlnktvkirqggykgkigivkeangdrfrvelhnpnktipipcsflliesthgwvpyed
interface signature	MKPTAR/D//V

Estimated binding specificities ?

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# IC=3.664 IC/col=0.282 n_of_columns=13

specificity:

A |   0  14  24  24  24  24  24  24  24  24  21   2  92
C |  96  14  24  24  24  24  24  24  24  24  23   4   2
G |   0  16  24  24  24  24  24  24  24  24  31   2   1
T |   0  52  24  24  24  24  24  24  24  24  21  88   1

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updated Sun Dec 15 18:17:16 2024