7xn7_ABEW : 3D-footprint complex

structure name	RNA POLYMERASE II ELONGATION COMPLEX CONTAINING SPT4/5, ELF1, SPT6, SPN1 AND PAF1C
experiment	NMR
structural superfamily	Translation proteins SH3-like domain;
reference complex	5xon_W 7xn7_u
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7xn7_A interface=239,304,435,818,819,1338, sqfpyssaplrsvkevqfgllspeeiraisvvkieypeimdesrqrpregglndpklgsidrnfkcqtcgegmaecpghfghmelakpvfhigfipkikkvcecicmncgkllldetnptmaqairirdpkkrfnavwqlcktkmvceadapvsrggcgntqpvvrkdgmklwgtwkksrdaqperklltpgeilnvfkhispedcfrlgfnedyarpewmiitvlpvpppqvrpsiaMdettqgqddlthklsdilkaninvqklemdgspqhiineveqllqfhvatymdndiagqpqalqKsgrpvkairarlkgkegrlrgnlmgkrvdfsartvisgdpnleldqvgvpisiaktlsypetvtqynihrlteyvrngpnehpgakyvirdngdridlryhkragdivlqygwkverhlmdddpvlfnrqPslhkmsmmahrvkvmpystfrlnlsvtspynadfdgdemnlhvpqseetraelsqlcavplqivspqsnkpvmgivqdtlcgvrkmtlrdtfieyeqvmnmlfwvpswdgvvpqpailkpkplwtgkqllsiaipsgihlqrtdggnsllspkdngmlivdgkvmfgvvdkktvgsgggglihtvmrekgpkicaelfgniqkvvnywllhngfsigigdaiadastmkeithaissakeqvqeiiykaqhnelelkpgmtlresfegevsrtlndardsagrsaemnlkdlnnvkqmvsagskgsfiniaqmsacvgqqmvegkriafgfadrslphftkddfspeskgfvensylrgltpqefffhamagreglidtavkTAetgyiqrrlvkaledimvhydgttrnslgdiiqflygedgldgtqverqtidtipgsdkafhkryyvdlmdeknsikpdvieyaadilgdvelqkelnseyeqlvsdrkflreivfvngdhnwplpvnlrriiqnaqqifhldrakasdltipeiihgvrdlckklfvlrgenelikeaqqnatslfqclvrarlatrrileefrlnrdafewvlgtieaqfqrslvhpgemvgviaaqsigepatqmnvtlgvprlkeilnvakniktpaltvyldreialdiekakviqssieyttlknvtsateiyydpdptstvieedfdtveayfsqspwllrleldrarmldkqltmnqvadkisevfsddlfvmwsednadkliircrvieedqmlkrieahmldlialrgipgiskvymvkhkvsvpdesgeykneelwaletdginlaevmavpgvdssrtysnsfveilsvlgieatrsslykeilnviafdgsyvnyrhmallvdvmtsrgylmaitRhginradtgalmrcsfeetveilfeagaaaelddcrgvsenvmlgqlapmgtgafdvmidekllts > 7xn7_B interface=462, ddtittedcwtvisaffeekglvsqqldsfdefmetsiqdlvweeprlildqpaqhdninkryeirfgkiylsrptmteadgtthamfpqearlrnltysspvyldmeksmftsidgnkvhigkvpimlrskfcslrtldevdlykmkecpydmggyfvingsekvliaqersaanivqvfkkaapspishvaeirsalekgsrlistmqiklygredkgtgrtikatlpyvkqdipivivfralgvvpdgeilqhicydendwqmlemlkpcieegfviqdkevaldfigrrgsaalgirrekriqyakdilqkellphitqeegfetrktfflgymvnrlllcalerkdqddrdhfgkkrldlagpllanlfrilfrkltreiyrymqrcietdrdfnlnlavksttitsglkyslatgnwgeqkkamssragvsqvlnrytysstlshlrrtntpigrDgklakprqlhnthwglvcpaetpegqacglvknlsllsgisigspsepiinfleewgmepledydpaqhtkstrifvngvwtgihrdpsmlvstmrdlrrsgaispevsiirdirerefkiftdvgrvyrplfiveddeskdnkgelritkehirkiqqgydddvygwsslvtsgvieyvdgeeeetimiamtpedlqtndtakrikpemstsshhtfthceihpsmilgvaasiipfpdhnqsprntyqsamgkqamgvfltnynvrmdtmanilyypqkplaktqameylkfrelpagqnaivaiacysgynqedsmimnqssidrglfrslffrsymdqekrfgisiveefekptrattlrlkhgtyekldedgliapgvrvsgddiiigkttpippdteelgqrtkyhtkrdastplrstengivdqvllttnqeglkfvkvrmrttkvpqigdkfasrhgqkgtigvtyrhedmpfsaegivpdliinphaipsrmtvahliecllskvgsirgyegdatpftdltvdavsnllrdngyqsrgfevmynghtgkklmaqvffgptyyqrlrhmvddkiharargpvqvltrqpvegrsrdgglrfgemerdcmiahgaagflkerlmeasdafrvhvcgicglmsvianlkknqfecrscknktniyqlhipyaakllfqelmamniaprlytersg > 7xn7_E interface= ednnriisrlwrsfrtvkemaadrgyfisqeemdqsleefrskicdsmgnpqrklmsflanptpealekysdlgtlwvefcdepsvgiktmrnfclriqeknfstgifiyqnnitpsankmiptvspaiietfqesdlvvnithhelvpkhirlsdgeksqllqryklkesqlpriqredpvarylglkrgqvvkiirrsetsgryasyricl > 7xn7_W interface= pqrlliptvddpgiwgvkvrlgkekdvvrqilkkklaregtknpleiysafqrdsfkghvyiearkaeaindalkgnvnvfsnnskflvgiveykdllrpvkssdvkltrgsyvrvkngkfkgdlaqvdevlenglearlklvprldygfrpaqrlfseaearvheptirrdrdgfvtyggeeyyegflyktfrlqnlivnsinptlnelslfqsneesttidlstiadslketaknlvsfqpgdnveiingelnhltgtvssvnqstivsvrlhsdddtinsetveiptsdlrkifnvgdhvrvihgkhtddtglivevngdkvefisnqtkrtvivfsnylikstdstvsinesgrfelhdlvqvnsdlvgiviraqkdsfdvlcsdgkllslppvsiysklnlnpnqqiaidsngvevkvgdtvreftgerrqgtilhvyrnflflrsreivenqgvfVtssnrvktirdptlnktvkirqggykgkigivkeangdrfrvelhnpnktipipcsflliesthgwvpyed
interface signature	MKPTAR/D//V

Estimated binding specificities ?

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# IC=3.481 IC/col=0.268 n_of_columns=13

specificity:

A |   0  85  21  24  24  24  24  24  24  24  24  16  90
C |   0   3  31  24  24  24  24  24  24  24  24  52   2
G |   0   5  21  24  24  24  24  24  24  24  24  14   2
T |  96   3  23  24  24  24  24  24  24  24  24  14   2

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updated Wed Jan 7 14:47:45 2026