7yq3_EF : 3D-footprint complex

structure name	HUMAN INSULIN RECEPTOR BOUND WITH A43 DNA APTAMER AND INSULIN
experiment	NMR
structural superfamily	L domain-like;Fibronectin type III;Growth factor receptor domain;
reference complex	7yq3_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7yq3_E interface=469,480,543,546,668, hlypgevcpgmdirnnltrlhelencsvieghlqillmfktrpedfrdlsfpklimitdylllfrvygleslkdlfpnltvirgsrlffnyalvifemvhlkelglynlmnitrgsvrieknnelcylatidwsrildsvednhivlnkddneecgdicpcpatvingqfvercwthshcqkvcptickshgctaeglcchseclgncsqpddptkcvacrnfyldgrcvetcpppyyhfqdwrcvnfsfcqdlhhkcknsrrqgchqyvihnnkcipecpsgytmnssnllctpclgpcpkvchllegektidsvtsaqelrgctvingsliinirggnnlaaeleanlglieeisgylkirrsyalvslsffrklrlirgetleignysfyaldnqnlrqlwdwskhnltttqgklffhynpklclseihkmeevsgtkgrqerndialktngdkascenellkfsYirtsfdkillRwepywppdfrdllgfmlfykeapyqnvtefdgqdacgsnswtvvdidpplrsndpksqnhpgWlmRglkpwtqyaifvktlvtfsderrtygaksdiiyvqtdatnpsvpldpisvsnsssqiilkwkppsdpngnithylvfwerqaedselfeldyclkglklpscscpktdsqilkeleessfrKtfedylhnvvhrpfekvvnkeslvisglrhftgyrielqacnqdtpeercsvaayvsartmpeakaddivgpvtheifennvvhlmwqepkepnglivlyevsyrrygdeelhlcvsrkhfalergcrlrglspgnysvriratslagngswteptyfyvtd > 7yq3_F interface=261,262,315, pgevcpgmdirnnltrlhelencsvieghlqillmfktrpedfrdlsfpklimitdylllfrvygleslkdlfpnltvirgsrlffnyalvifemvhlkelglynlmnitrgsvrieknnelcylatidwsrildsvednhivlnkddneecgdicpncpatvingqfvercwthshcqkvcptickshgctaeglcchseclgncsqpddptkcvacrnfyldgrcvetcpppyyhfqdwrcvnfsfcqdlhhkcknsrRQgchqyvihnnkcipecpsgytmnssnllctpclgpcpkvchllegektidsvTsaqelrgctvingsliinirggnnlaaeleanlglieeisgylkirrsyalvslsffrklrlirgetleignysfyaldnqnlrqlwdwskhnltttqgklffhynpklclseihkmeevsgtkgrqerndialktngdkascenellkfsyirtsfdkillrwepywppdfrdllgfmlfykeapyqnvtefdgqdacgsnswtvvdidpplrsndpksqnhpgwlmrglkpwtqyaifvktlvtfsderrtygaksdiiyvqtdatnpsvpldpisvsnsssqiilkwkppsdpngnithylvfwerqaedselfeldyclkglklcscpktdsqilkeleessfrktfedylhnvvfvprphrpfekvvnkeslvisglrhftgyrielqacnqdtpeercsvaayvsartmpeakaddivgpvtheifennvvhlmwqepkepnglivlyevsyrrygdeelhlcvsrkhfalergcrlrglspgnysvriratslagngswteptyfyvtd
interface signature	YRWRK/RQT

Estimated binding specificities ?

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# IC=5.339 IC/col=0.445 n_of_columns=12

specificity:

A |   0   0  24  24   9  24  24   9   9  24  24   0
C |  96   0  24  24   9  24  24   9   9  24  24  96
G |   0  96  24  24  67  24  24  69  67  24  24   0
T |   0   0  24  24  11  24  24   9  11  24  24   0

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updated Fri Aug 1 02:48:17 2025